The splanchnic anti-inflammatory pathway has been proposed as the efferent arm of the inflammatory reflex. While much evidence points to the spleen as the principal target organ where sympathetic nerves inhibit immune function, a systematic study to locate the target organ(s) of the splanchnic anti-inflammatory pathway has not yet been made. In anaesthetised rats made endotoxemic with lipopolysaccharide (LPS, 60\ub5g/Kg i.v.), plasma levels of tumor necrosis factor \u3b1 (TNF) were measured in animals with cut (SplancX) or sham-cut (Sham) splanchnic nerves. We confirm here that disengagement of the splanchnic anti-inflammatory pathway in SplancX rats (17.01\ub10.95 ng/ml) strongly enhances LPS-induced plasma TNF levels compared to Shams (3....
Fulltext embargoed for: 12 months post date of publicationThe 'inflammatory reflex' acts through eff...
Metabolic disorders have been identified as major health problems affecting a large portion of the w...
Evidence indicates that the activation of the parasympathetic branch of the autonomic nervous system...
The splanchnic anti-inflammatory pathway has been proposed as the efferent arm of the inflammatory r...
We investigated a neural reflex that controls the strength of inflammatory responses to immune chall...
Following an immune challenge, there is two-way communication between the nervous and immune systems...
The splanchnic anti-inflammatory pathway, the efferent arm of the endogenous inflammatory reflex, ha...
What is the topic of this review? We review the current literature on the neural reflex termed the '...
From a critical review of the evidence on the cholinergic anti-inflammatory pathway and its mode of ...
The brain plays a prominent role in the regulation of inflammation. Immune cells are under control o...
The 'inflammatory reflex' acts through efferent neural connections from the central nervous system t...
Animal studies have demonstrated that various secondary lymphoid organs (including the spleen and ly...
Acetylcholine is the main transmitter of the parasympathetic vagus nerve. According to the cholinerg...
Fulltext embargoed for: 12 months post date of publicationThe 'inflammatory reflex' acts through eff...
Metabolic disorders have been identified as major health problems affecting a large portion of the w...
Evidence indicates that the activation of the parasympathetic branch of the autonomic nervous system...
The splanchnic anti-inflammatory pathway has been proposed as the efferent arm of the inflammatory r...
We investigated a neural reflex that controls the strength of inflammatory responses to immune chall...
Following an immune challenge, there is two-way communication between the nervous and immune systems...
The splanchnic anti-inflammatory pathway, the efferent arm of the endogenous inflammatory reflex, ha...
What is the topic of this review? We review the current literature on the neural reflex termed the '...
From a critical review of the evidence on the cholinergic anti-inflammatory pathway and its mode of ...
The brain plays a prominent role in the regulation of inflammation. Immune cells are under control o...
The 'inflammatory reflex' acts through efferent neural connections from the central nervous system t...
Animal studies have demonstrated that various secondary lymphoid organs (including the spleen and ly...
Acetylcholine is the main transmitter of the parasympathetic vagus nerve. According to the cholinerg...
Fulltext embargoed for: 12 months post date of publicationThe 'inflammatory reflex' acts through eff...
Metabolic disorders have been identified as major health problems affecting a large portion of the w...
Evidence indicates that the activation of the parasympathetic branch of the autonomic nervous system...