The invention relates to thermochemiluminescent silica nanoparticles containing in dispersion in the silica matrix molecules of a thermochemiluminescent acridine-based 1,2-dioxetane and additional chemical species, such as a fluorescent energy acceptor with the function of improving the efficiency of the thermochemiluminescent reaction and/or modifying the emission wavelength, and a method for the synthesis thereof. The nanoparticles are functionalized on the surface with reactive groups (e.g. amines) and procedures are described for bonding them to biospecific probes (e.g. antibodies) and enabling their use as thermochemiluminescent markers in bioanalytical methods (e.g. immunometric methods) based on thermochemi luminescence measurements
To create bright and stable fluorescent biolabels for immunoassay detection of mycotoxin deoxynivale...
Modern approaches to biological and biomedical analysis demand ever-increasing levels of sensitivity...
Click on the DOI link to access the article (may not be free).Fluorescent silica nanoparticles (FSNs...
The invention relates to thermochemiluminescent silica nanoparticles containing in dispersion in the...
Thermochemiluminescence (TCL; the light emission originating by the thermally triggered decompositio...
Doped organically modified silica nanoparticles (ORMOSIL NPs) with luminescent molecules represent a...
A new chemiluminescent system is developed in which inherently chemiluminescent compounds—that is, s...
AbstractDye-entrapped silica nanoparticles can be used to label biological components in immunosensi...
Fluorescent silica nanoparticles have been extensively utilised in a broad range of biological appli...
Silica based luminescent nanoparticles provide tremendous potential as biocompatible and robust inor...
International audienceThe design of nanomaterials that are capable of specific and sensitive biomole...
The field of nanoparticles is amazingly many-sided and consequently their applications range between...
There are a wide variety of silica nanoformulations being investigated for biomedical applications. ...
The production of uniform protein-binding biofunctional fluorescent spherical silica core-shell nano...
The ability to find synergic solutions is the core of scientific research and scientific advancement...
To create bright and stable fluorescent biolabels for immunoassay detection of mycotoxin deoxynivale...
Modern approaches to biological and biomedical analysis demand ever-increasing levels of sensitivity...
Click on the DOI link to access the article (may not be free).Fluorescent silica nanoparticles (FSNs...
The invention relates to thermochemiluminescent silica nanoparticles containing in dispersion in the...
Thermochemiluminescence (TCL; the light emission originating by the thermally triggered decompositio...
Doped organically modified silica nanoparticles (ORMOSIL NPs) with luminescent molecules represent a...
A new chemiluminescent system is developed in which inherently chemiluminescent compounds—that is, s...
AbstractDye-entrapped silica nanoparticles can be used to label biological components in immunosensi...
Fluorescent silica nanoparticles have been extensively utilised in a broad range of biological appli...
Silica based luminescent nanoparticles provide tremendous potential as biocompatible and robust inor...
International audienceThe design of nanomaterials that are capable of specific and sensitive biomole...
The field of nanoparticles is amazingly many-sided and consequently their applications range between...
There are a wide variety of silica nanoformulations being investigated for biomedical applications. ...
The production of uniform protein-binding biofunctional fluorescent spherical silica core-shell nano...
The ability to find synergic solutions is the core of scientific research and scientific advancement...
To create bright and stable fluorescent biolabels for immunoassay detection of mycotoxin deoxynivale...
Modern approaches to biological and biomedical analysis demand ever-increasing levels of sensitivity...
Click on the DOI link to access the article (may not be free).Fluorescent silica nanoparticles (FSNs...