Osteosarcoma of the pelvis: A monoinstitutional experience in patients younger than 41 years
- FERRARI, STEFANO
- PALMERINI, EMANUELA
- FABBRI, NICOLA
- STAALS, ERIC LODEWIJK
- ALBERGHINI, MARCO
- PICCI, PIERO
- Ferrari, Cristina
DOIAbstract
Aims and background. Information is scarce on systemic treatment of pelvic osteosarcoma because most chemotherapy protocols for osteosarcoma include patients with extremity tumors and aged up to 30-40 years. Methods. Data on patients <41 years of age with high-grade pelvic osteosarcoma were prospectively collected. Patients received two chemotherapy protocols consisting of methotrexate, cisplatin, doxorubicin (MAP) and standard-dose or high-dose ifosfamide. Results. Forty patients between 11 and 36 years were included. The most frequent histological subtype was osteoblastic followed by chondroblastic (37.5%). Complete surgical remission was achieved in 65% of patients. Eighteen patients had MAP/standard- dose ifosfamide, 22 MAP/high-dose if...
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