Molecular Testing for Parvoviruses

none1noThe family Parvoviridae includes viruses with a single-stranded DNA genome, encapsidated in an icosahedral protein capsid, about 2226 nm in diameter. Replication occurs in the nucleus of infected cells and is highly dependent on cellular environment, so that a productive cycle is usually achieved only in actively replicating cells, or in some cases when supported by complementation from helper viruses. The subfamily Parvovirinae includes viruses able to infect vertebrate hosts, within it the most recent taxonomical revision distinguishes eight viral genera, and within each genus individual virus species that collect the viral isolates normally recognized in laboratory or clinical settings.noneGiorgio GallinellaGiorgio Gallinell