New insights into orthostatic hypotension in multiple system atrophy: A European multicentre cohort study
- Pavy-Le Traon, A
- Piedvache, A
- Perez-Lloret, S
- Calandra-Buonaura, G
- Cochen-De Cock, V
- Colosimo, C
- Cortelli, P
- Debs, R
- Duerr, S
- Fanciulli, A
- Foubert-Samier, A
- Gerdelat, A
- Gurevich, T
- Krismer, F
- Poewe, W
- Tison, F
- Tranchant, C
- Wenning, G
- Rascol, O
- Meissner, W G.
- European MSA Study Group.
Publication date
January 2016
DOI Publisher
BMJ ISSN
0022-3050 Citation count (estimate)
17Abstract
Orthostatic hypotension (OH) is a key feature of multiple system atrophy (MSA), a fatal progressive neurodegenerative disorder associated with autonomic failure, parkinsonism and ataxia. This study aims (1) to determine the clinical spectrum of OH in a large European cohort of patients with MSA and (2) to investigate whether a prolonged postural challenge increases the sensitivity to detect OH in MSA
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