HFE gene variants and iron-induced oxygen radical generation in idiopathic pulmonary fibrosis
- Sangiuolo F
- Puxeddu E
- Pezzuto G
- Cavalli F
- Longo G
- Comandini A
- Di Pierro D
- Pallante M
- Sergiacomi G
- Simonetti G
- Orlandi A
- Magrini A
- Amicosante M
- Mariani F
- Losi M
- Fraboni D
- Bisetti A
- Saltini C.
- ZOMPATORI, MAURIZIO
Publication date
January 2015
DOIAbstract
The data suggest iron dysregulation associated with HFE allelic variants may play an important role in increasing susceptibility to environmental exposures, leading to recurring injury and fibrosis in IP
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