Colorectal cancer genetics: Implications for diagnosis, treatment and surveillance [Genetica del carcinoma colorettale: Implicazioni per la diagnosi, la terapia e la sorveglianza]

The identification of the genetic bases of hereditary colorectal cancers has made possible to identify the syndromes but also to generate molecular models relevant for the sporadic type of cancers. This has progressively led to the adoption of genetic and molecular tests which play a key role in the clinical and therapeutic management of patients with the disease