Ketamine (2-(2-chlorophenyl)-2-(methylamino)cyclohexanone) is a human and veterinary anaesthetic and analgesic with hallucinogenic properties. For this reason it is illegally used for recreational purposes and included in the controlled substance schedules of most countries. The compound possesses a stereogenic asymmetric carbon atom and can exist as a pair of enantiomers. Pharmacological studies have demonstrated that the S-(+)-enantiomer of ketamine is about three times more potent than the R-(–)-enantiomer as an analgesic. Currently, most ketamine formulations are racemic, however enantiopure S-ketamine is also available on the market under the brand name "Ketanest S". On the other hand, even if ketamine hallucinogenic potency is still l...
Ketamine is an anaesthetic agent that is being increasingly used at sub-anaesthetic doses as an anal...
Drug abuse is a severe social problem, expecially among young people, which can cause devastating im...
Recognizing that the stereochemical structure of NMDA receptor antagonist ketamine provides valuable...
Ketamine (2-(2-chlorophenyl)-2-(methylamino)cyclohexanone) is a human and veterinary anaesthetic and...
Ketamine ((R,S-2-(2-chlorophenyl)-2-methylamino)cyclohexanone) is a phencyclidine derivative used in...
Ketamine, an injectable anesthetic and analgesic consisting of a racemic mixture of S-and R-ketamine...
The chiral drug ketamine has long-lasting antidepressant effects with a fast onset and is also suita...
The chiral drug ketamine has long-lasting antidepressant effects with a fast onset and is also suita...
Ketamine is an anaesthetic drug, which since 1980s has spread also as an abusedpsychoactive substanc...
CE with multiple isomer sulfated beta-CD as the chiral selector was assessed for the simultaneous an...
Aims: Ketamine is a dissociative anaesthetic traditionally available as a racemic mixture, although,...
Glucuronidation catalyzed by uridine-5'-diphospho-glucuronosyl-transferases (UGTs) is the most impor...
Ketamine is a widely used dissociative drug, whose quantification in plasma and urine can be of phar...
Ketamine, a phencyclidine derivative, is used for induction of anesthesia, as an anesthetic drug for...
Chiral metabolites of ketamine exerting rapid-onset yet sustained antidepressant effects may be mark...
Ketamine is an anaesthetic agent that is being increasingly used at sub-anaesthetic doses as an anal...
Drug abuse is a severe social problem, expecially among young people, which can cause devastating im...
Recognizing that the stereochemical structure of NMDA receptor antagonist ketamine provides valuable...
Ketamine (2-(2-chlorophenyl)-2-(methylamino)cyclohexanone) is a human and veterinary anaesthetic and...
Ketamine ((R,S-2-(2-chlorophenyl)-2-methylamino)cyclohexanone) is a phencyclidine derivative used in...
Ketamine, an injectable anesthetic and analgesic consisting of a racemic mixture of S-and R-ketamine...
The chiral drug ketamine has long-lasting antidepressant effects with a fast onset and is also suita...
The chiral drug ketamine has long-lasting antidepressant effects with a fast onset and is also suita...
Ketamine is an anaesthetic drug, which since 1980s has spread also as an abusedpsychoactive substanc...
CE with multiple isomer sulfated beta-CD as the chiral selector was assessed for the simultaneous an...
Aims: Ketamine is a dissociative anaesthetic traditionally available as a racemic mixture, although,...
Glucuronidation catalyzed by uridine-5'-diphospho-glucuronosyl-transferases (UGTs) is the most impor...
Ketamine is a widely used dissociative drug, whose quantification in plasma and urine can be of phar...
Ketamine, a phencyclidine derivative, is used for induction of anesthesia, as an anesthetic drug for...
Chiral metabolites of ketamine exerting rapid-onset yet sustained antidepressant effects may be mark...
Ketamine is an anaesthetic agent that is being increasingly used at sub-anaesthetic doses as an anal...
Drug abuse is a severe social problem, expecially among young people, which can cause devastating im...
Recognizing that the stereochemical structure of NMDA receptor antagonist ketamine provides valuable...