From Transient to Induced Permanent Chirality in 2-Propanol upon Dimerization: A Rotational Study

Five different hydrogen bonded conformers of the dimer of 2-propanol have been characterized by Fourier transform microwave spectroscopy. In all observed species the proton donor moiety adopts a gauche conformation. While in the gauche-monomer a transient chirality takes place, all dimers are classical chiral systems. The Ubbelohde effect has been observed upon OH  OD isotopic substitution and its structural effects – a 5 mÅ reduction of the O---O distance – quantitatively defined