none11nonePellagatti A; Marafioti T; Paterson JC; Barlow JL; Drynan LF; Giagounidis A; Pileri SA; Cazzola M; McKenzie AN; Wainscoat JS; Boultwood J.Pellagatti A; Marafioti T; Paterson JC; Barlow JL; Drynan LF; Giagounidis A; Pileri SA; Cazzola M; McKenzie AN; Wainscoat JS; Boultwood J
A haploid genotype may be insufficient to support nonnal wild-type function. Such haplo-insufficienc...
<p>Canonical pathways in the table were significantly enriched (<i>P</i><0.05) among the regulatory ...
Summary: The p53 tumor suppressor pathway is frequently inactivated in human cancers. However, there...
We have demonstrated induction of p53 and up-regulation of the p53 pathway in the human 5q– syndrome...
In recent years we have gained great insight into the molecular pathogenesis of the 5q- syndrome, th...
In recent years we have gained great insight into the molecular pathogenesis of the 5q- syndrome, a ...
The identification of the genes associated with chromosomal translocation breakpoints has fundamenta...
Clonal heterogeneity has not been described in patients with myelodysplastic syndrome with isolated ...
The identification of the genes associated with chromosomal translocation breakpoints has fundamenta...
The 5q- syndrome is a distinct hematological disorder with typical laboratory, morphological, cytoge...
Little is known about the relationship between the 5q- syndrome and the other subtypes of MDS, prima...
<p>(A, B) p53 regulates Sirt3 level. Sirt3 expression at RNA (A) and protein level (B) were measured...
<p>A. Left panel: QRT-PCR of p65RelA RNA level in H1299 tet-inducible p53 (P72 variant) cells follow...
<p>In pluripotent hESCs, p53 is negatively regulated by HDM2 and TRIM24. Differentiation induces ace...
学位の種別: 課程博士審査委員会委員 : (主査)東京大学准教授 松田 浩一, 東京大学教授 菅野 純夫, 東京大学教授 古川 洋一, 東京大学准教授 加藤 直也, 東京大学講師 松原 大
A haploid genotype may be insufficient to support nonnal wild-type function. Such haplo-insufficienc...
<p>Canonical pathways in the table were significantly enriched (<i>P</i><0.05) among the regulatory ...
Summary: The p53 tumor suppressor pathway is frequently inactivated in human cancers. However, there...
We have demonstrated induction of p53 and up-regulation of the p53 pathway in the human 5q– syndrome...
In recent years we have gained great insight into the molecular pathogenesis of the 5q- syndrome, th...
In recent years we have gained great insight into the molecular pathogenesis of the 5q- syndrome, a ...
The identification of the genes associated with chromosomal translocation breakpoints has fundamenta...
Clonal heterogeneity has not been described in patients with myelodysplastic syndrome with isolated ...
The identification of the genes associated with chromosomal translocation breakpoints has fundamenta...
The 5q- syndrome is a distinct hematological disorder with typical laboratory, morphological, cytoge...
Little is known about the relationship between the 5q- syndrome and the other subtypes of MDS, prima...
<p>(A, B) p53 regulates Sirt3 level. Sirt3 expression at RNA (A) and protein level (B) were measured...
<p>A. Left panel: QRT-PCR of p65RelA RNA level in H1299 tet-inducible p53 (P72 variant) cells follow...
<p>In pluripotent hESCs, p53 is negatively regulated by HDM2 and TRIM24. Differentiation induces ace...
学位の種別: 課程博士審査委員会委員 : (主査)東京大学准教授 松田 浩一, 東京大学教授 菅野 純夫, 東京大学教授 古川 洋一, 東京大学准教授 加藤 直也, 東京大学講師 松原 大
A haploid genotype may be insufficient to support nonnal wild-type function. Such haplo-insufficienc...
<p>Canonical pathways in the table were significantly enriched (<i>P</i><0.05) among the regulatory ...
Summary: The p53 tumor suppressor pathway is frequently inactivated in human cancers. However, there...