Assessment of cognitive performance among Mexican children and adolescents afflicted by simple to complex congenital heart diseases. Preliminary study

Among patients afflicted by congenital heart diseases (CHD) diverse, and complex neurological alterations are commonly observed. These have neither been completely identified nor understood. With the aim of identifying specific neurocognitive alterations among children and adolescents afflicted by CHD we investigated the possible presence of cognitive disorders related to the presence of cardiovascular disease with the aid of a sample of 20 patients (12 teenagers and 8 school-age children). Taken altogether, 9 of them were afflicted by simple and 11 by complex pathologies (respectively, CHDs/c). The Neuropsychological Test for Memory and Attention (Neuropsi), standardized for Mexico by Ostrosky et al. (2004), was individually applied to all participants. The information of cognitive performance was obtained in relation to the categories attention and memory, and the same areas allowed us to assess global performance. CHDc subjects performed significantly poorer compared to CHDs in i) attention and executive function, ii) memory and iii) attention and memory. Likewise, among CHDc subjects a significantly higher proportion of cases were diagnosed as abnormal in the same variables. Also a significant and negative correlation was determined between CHD severity and neuropsychological scoring. Children and adolescents afflicted by CHD are at high risk of developing cognitive function alterations including aspects of memory, attention and executive functions, alterations which are likely to be worst among those cases carrying CHDc conditions