Nanostructured polymeric functional micelles for drug delivery applications

  • TRIPODO, GIUSEPPE
  • DORATI, ROSSELLA
  • GENTA, IDA
  • CONTI, BICE
  • Mandracchia D.
  • Latrofa A.
Publication date
January 2013

Abstract

In this work the hydrophobic core of Inulin based micelles has been exploited for the loading of the model hydrophobic drug curcumin (solubility ≈ 11ng/ml), the drug release studies have been performed in simulated physiological fluids. Furthermore, biological studies on suitable cell lines have been performed to verify the biocompatibility of INVITE conjugates

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Topics

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curcuminChemical substance
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InulinChemical substance
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hydrophobicBuilding
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