none9Although Peyer’s patches (PPs) and the enteric nervous system (ENS) play a key role in early sheep scrapie pathogenesis, little is known on the kinetics of ENS plexuses colonization. This study was aimed at quali-quantitatively evaluating ileal PP innervation in 29 Sarda breed ovines (12 scrapie-free, 2 months-old lambs, 4 ARQ/ARQ, 4 ARR/ARQ and 4 ARR/ARR, respectively; 12 scrapie-free, 2-4 years-old sheep, 3 ARQ/ARQ, 7 ARR/ARQ and 2 ARR/ARR, respectively; 5 ARQ/ARQ scrapie-affected sheep). Terminal ileum was collected and processed for routine histology from all animals under study. Ileal PP innervation was immunohistochemically evaluated by means of an anti-PgP9.5 (pan-neuronal marker) polyclonal antibody (Ab) and of an anti-TH ...
none8After oral scrapie challenge, one of the early infection targets is the enteric nervous system ...
The pathogenesis of scrapie infection was studied in sheep carrying the PrPVRQ/PrPVRQ genotype, whic...
Until now, significant differences in the neurochemical pattern of enteric neurons have been demonst...
Although Peyer’s patches (PPs) and the enteric nervous system (ENS) play a key role in early sheep s...
none10Ileal Peyer's patches (PPs) are involved early during sheep scrapie infection. This study qual...
P03.133 Immunohistochemistry, Immunofluorescence and Confocal Laser Microscopy: An Insight into th...
none8Scrapie represents the prototype of transmissible spongiform encephalopathies, or prion disease...
Abstract. Transmission of sheep scrapie and some other prion diseases, including variant Creutzfeldt...
The enteric nervous system (ENS) probably plays a dominant role in sheep scrapie pathogenesis, but l...
The enteric nervous system (ENS) probably plays a dominant role in sheep scrapie pathogenesis, but ...
Disease-associated prion protein (PrPd) in the enteric nervous system (ENS) of 20- to 24-month-old S...
Until now, significant differences in the neurochemical pattern of enteric neurons have been demons...
none7Although scrapie is extensively investigated in laboratory rodents, it is not a spontaneous dis...
none16noneMarruchella G.; Ligios C.; Uras P.; Zucca R.; Lalatta-Costerbosa G.; Chiocchetti R.; Clave...
none8After oral scrapie challenge, one of the early infection targets is the enteric nervous system ...
The pathogenesis of scrapie infection was studied in sheep carrying the PrPVRQ/PrPVRQ genotype, whic...
Until now, significant differences in the neurochemical pattern of enteric neurons have been demonst...
Although Peyer’s patches (PPs) and the enteric nervous system (ENS) play a key role in early sheep s...
none10Ileal Peyer's patches (PPs) are involved early during sheep scrapie infection. This study qual...
P03.133 Immunohistochemistry, Immunofluorescence and Confocal Laser Microscopy: An Insight into th...
none8Scrapie represents the prototype of transmissible spongiform encephalopathies, or prion disease...
Abstract. Transmission of sheep scrapie and some other prion diseases, including variant Creutzfeldt...
The enteric nervous system (ENS) probably plays a dominant role in sheep scrapie pathogenesis, but l...
The enteric nervous system (ENS) probably plays a dominant role in sheep scrapie pathogenesis, but ...
Disease-associated prion protein (PrPd) in the enteric nervous system (ENS) of 20- to 24-month-old S...
Until now, significant differences in the neurochemical pattern of enteric neurons have been demons...
none7Although scrapie is extensively investigated in laboratory rodents, it is not a spontaneous dis...
none16noneMarruchella G.; Ligios C.; Uras P.; Zucca R.; Lalatta-Costerbosa G.; Chiocchetti R.; Clave...
none8After oral scrapie challenge, one of the early infection targets is the enteric nervous system ...
The pathogenesis of scrapie infection was studied in sheep carrying the PrPVRQ/PrPVRQ genotype, whic...
Until now, significant differences in the neurochemical pattern of enteric neurons have been demonst...