In vitro antibacterial activity of different self-etch adhesives

Purpose: The aim of this study was to evaluate and compare the antimicrobial activity of different self- etch adhesives by means of the agar disc diffusion test. Methods: Streptococcus salivarius, Streptococcus sanguis and Streptococcus mutans strains were selected to evaluate the antimicrobial activity of various self-etch adhesives (Futurabond NR, G-aenial Bond, AdperTM Easy Bond Self-Etch Adhesive, Clearfil Protect Bond, One Coat 7.0, Clearfil S3 Bond, Clearfil SE Bond) using the agar disc diffusion test; 0.2% Chlorexidine digluconate was used as con- trol. Paper disks were saturated with 10 μL of each adhesive system and placed onto culture agar plates pre-adsorbed with bacterial cells and further incubated for 24 h at 37°C. The growth inhibition zones around each adhesive were recorded and compared for each bacterial strain. Results: The test results of the various self-etch adhesives were significantly different. Conclusions: The results of the present investigation showed that the addition of MDPB monomer to an adhesive system enhances its antibacterial effect against S. salivarius, S. sanguis and S. mutans