Add to ORKGTrimethoprim [5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4diamine, TMP] interacts with one sulfadimidine [4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide, SDMD] molecule through two hydrogen bonds forming an eight membered ring, as in the 1:1 methanolate complex, with no proton transfer from the imino sulfonamide N atom to the pyrimidine N atom of the partner. Association with the second sulfadimidine molecule (SDMD') occurs through an interaction involving the same pyrimidine N atom of TMP (which therefore acts as a double acceptor) and the NH imino group of the sulfonamide. The water molecule bridges the sulfonamido O atom and the p-aminophenyl group of SDMD' of two molecular complex units
In the asymmetric unit of the title co-crystal, C12H14N4O2S·C7H5NO4, the sulfamethazine and 2-nitrob...
In the asymmetric unit of the title co-crystal, C12H14N4O2S·C7H5NO4, the sulfamethazine and 2-n...
In the asymmetric unit of the title co-crystal, C12H14N4O2S·C7H5NO4, the sulfamethazine and 2-nitrob...
In the title compound, trimethoprim trifluoroacetate [or 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrim...
Proton transfer to the sulfa drug sulfadiazine [systematic name: 4-amino-N-(pyrimidin-2-yl)benzenesu...
In the structure of the of the phenolate salt of the sulfa drug sulfamethazine with 3,5-dinitrosalic...
In the asymmetric unit of the title co-crystal, C12H14N4O2S . C7H5NO4 there are two independent but ...
The 1: 1 molecular adducts of 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide (Sulfamethazi...
In the title 1:1 co-crystal, C9H10N4O2S2·C6H9N3O2 [systematic name: 4-amino-N-(5-methyl-1,3,4-thiadi...
In the title compound, C13H15N5O2S, the acetamide N—C(=O)—C plane makes dihedral angles of 30.51 (11...
disorder in main residue; R factor = 0.077; wR factor = 0.170; data-to-parameter ratio = 15.6. The a...
In the title compound, C18H18N4O4S2, the mean planes passing through the tosyl benzene rings form di...
In recrystallization experiments of sulphadimidine from water, dioxane and their mixtures aimed at p...
In the asymmetric unit of the title co-crystal, C7H5NO4·C12H14N4O2S, there are two independ...
R factor = 0.046; wR factor = 0.116; data-to-parameter ratio = 17.6. In the title compound, C18H18N4...
In the asymmetric unit of the title co-crystal, C12H14N4O2S·C7H5NO4, the sulfamethazine and 2-nitrob...
In the asymmetric unit of the title co-crystal, C12H14N4O2S·C7H5NO4, the sulfamethazine and 2-n...
In the asymmetric unit of the title co-crystal, C12H14N4O2S·C7H5NO4, the sulfamethazine and 2-nitrob...
In the title compound, trimethoprim trifluoroacetate [or 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrim...
Proton transfer to the sulfa drug sulfadiazine [systematic name: 4-amino-N-(pyrimidin-2-yl)benzenesu...
In the structure of the of the phenolate salt of the sulfa drug sulfamethazine with 3,5-dinitrosalic...
In the asymmetric unit of the title co-crystal, C12H14N4O2S . C7H5NO4 there are two independent but ...
The 1: 1 molecular adducts of 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide (Sulfamethazi...
In the title 1:1 co-crystal, C9H10N4O2S2·C6H9N3O2 [systematic name: 4-amino-N-(5-methyl-1,3,4-thiadi...
In the title compound, C13H15N5O2S, the acetamide N—C(=O)—C plane makes dihedral angles of 30.51 (11...
disorder in main residue; R factor = 0.077; wR factor = 0.170; data-to-parameter ratio = 15.6. The a...
In the title compound, C18H18N4O4S2, the mean planes passing through the tosyl benzene rings form di...
In recrystallization experiments of sulphadimidine from water, dioxane and their mixtures aimed at p...
In the asymmetric unit of the title co-crystal, C7H5NO4·C12H14N4O2S, there are two independ...
R factor = 0.046; wR factor = 0.116; data-to-parameter ratio = 17.6. In the title compound, C18H18N4...
In the asymmetric unit of the title co-crystal, C12H14N4O2S·C7H5NO4, the sulfamethazine and 2-nitrob...
In the asymmetric unit of the title co-crystal, C12H14N4O2S·C7H5NO4, the sulfamethazine and 2-n...
In the asymmetric unit of the title co-crystal, C12H14N4O2S·C7H5NO4, the sulfamethazine and 2-nitrob...