Cord blood derived endothelial progenitor cells: a superior buiding company in angiogenesis market.

Cervio M
Del Fante C
Malpasso G
Viarengo G
Perotti C.
GNECCHI, MASSIMILIANO

Publication date

January 2012

Abstract

Objective: Endothelial progenitor cells (EPCs) are a promising tool in regenerative medicine. We designed a comparative study of peripheral (adult, PB) versus umbilical cord blood (CB) derived EPCs in order to investigate the angiogenic properties of these two sources. Methods: Mononuclear cells (MNCs) were isolated from PB (n=4) and CB (<24 hours, n=4) and cultured on fibronectin-coated cell culture plates in endothelial cell culture medium until the formation of cobblestone-shaped colonies. Colony-derived cells were expanded for further investigation and their endothelial phenotype was confi rmed evaluating the uptake of Di-Iacetylated-low-density lipoprotein (Ac-LDL) and expression of endothelial cell-surface antigens (CD34, CD31, CD...

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Cord blood derived endothelial progenitor cells: a superior buiding company in angiogenesis market.

Abstract

Extracted data

Cord blood derived endothelial progenitor cells: a superior buiding company in angiogenesis market.

Abstract

Extracted data

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