This report describes a case of a malignant vascular tumor of the spleen with the morphologic, immunologic, and ultrastructural features observed in splenic sinus-lining cells (littoral cells). Histological examination showed a well-differentiated neoplasm forming ectatic blood channels with intraluminal papillary fronds. Tumor cells displayed malignant nuclear features and hemophagocytosis. Solid neoplastic areas with mitotic figures were present. Ultrastructurally, the tumor cells showed the concomitant presence of lysosomes and Weibel-Palade bodies. Immunohistochemically, the tumor cells were positive for both endothelial (Factor VIII-AG, CD34) and histiocytic markers (cathepsin D, lysozyme, alpha-1-antichimotrypsin). Our results indicat...
Primary angiosarcoma of the spleen is very rare and only 143 cases have previously been reported. Th...
Primary splenic angiosarcomas are the most common malignant non-hematopoietic tumors of the spleen. ...
Littoral cell angioma is a rare vascular tumor of the spleen that was described by Falk et al. in 19...
Littoral cell angioma is a rare primary vascular neoplasm of the spleen, composed of littoral cells ...
Vascular tumors of the spleen include several different entities, some of which are unique to that o...
Pathological examination in the spleen of an 81-year old female with hemoperitoneum, hypovolemic sh...
Primary splenic angiosarcoma is a rare malignant vascular neoplasm of mesenchymal origin. The tumor ...
Introduction. Primary splenic angiosarcoma is an extremely unusual neoplasm originating from sinusoi...
Littoral cell angioma is a rare primary vascular neoplasm of the spleen composed of blood-filled vas...
Angiosarcoma of the breast is a rare malignant sarcoma of endovascular origin that presents with va...
Primary splenic angiosarcoma carries a poor prognosis and is among the rarest forms of malignancy. A...
Littoral cell angioma is a rare vascular tumor of the spleen that was described by Falk et al. in 19...
Background. The spleen is mainly affected by benign tumors that originate from the vascular endothel...
Epitheloid angiosarcoma of the splenic capsula as a result of foreign body tumorigenesis. A case rep...
Splenic tumors are not frequent. Blood vessel neoplasms are a rare category of tumors and have an ex...
Primary angiosarcoma of the spleen is very rare and only 143 cases have previously been reported. Th...
Primary splenic angiosarcomas are the most common malignant non-hematopoietic tumors of the spleen. ...
Littoral cell angioma is a rare vascular tumor of the spleen that was described by Falk et al. in 19...
Littoral cell angioma is a rare primary vascular neoplasm of the spleen, composed of littoral cells ...
Vascular tumors of the spleen include several different entities, some of which are unique to that o...
Pathological examination in the spleen of an 81-year old female with hemoperitoneum, hypovolemic sh...
Primary splenic angiosarcoma is a rare malignant vascular neoplasm of mesenchymal origin. The tumor ...
Introduction. Primary splenic angiosarcoma is an extremely unusual neoplasm originating from sinusoi...
Littoral cell angioma is a rare primary vascular neoplasm of the spleen composed of blood-filled vas...
Angiosarcoma of the breast is a rare malignant sarcoma of endovascular origin that presents with va...
Primary splenic angiosarcoma carries a poor prognosis and is among the rarest forms of malignancy. A...
Littoral cell angioma is a rare vascular tumor of the spleen that was described by Falk et al. in 19...
Background. The spleen is mainly affected by benign tumors that originate from the vascular endothel...
Epitheloid angiosarcoma of the splenic capsula as a result of foreign body tumorigenesis. A case rep...
Splenic tumors are not frequent. Blood vessel neoplasms are a rare category of tumors and have an ex...
Primary angiosarcoma of the spleen is very rare and only 143 cases have previously been reported. Th...
Primary splenic angiosarcomas are the most common malignant non-hematopoietic tumors of the spleen. ...
Littoral cell angioma is a rare vascular tumor of the spleen that was described by Falk et al. in 19...