The major changes occurring life long in the human immune system are here described. The progressive inflammatory status which is established during aging together with the progressive susceptibility to infectious diseases are discussed in the frame of the genetic variant influence. Finally, the possibility to counteract the susceptibility to infections by coping with or slowing down immunosenescence, using different molecules or strategies, is argue
Human aging is a multifactorial phenomenon that affects numerous organ systems and cellular processe...
Background: Evolutionary theory and empirical evidence suggest that aging is a process of gradual ac...
Adaptive immunity undergoes severe deterioration with age and represents the main problem in the eld...
The major changes occurring life long in the human immune system are here described. The progressive...
Major advances in preventing, delaying, or curing individual pathologies are responsible for an incr...
In the elderly, many alterations of innate and acquired immunity have been described and viewed as d...
A dramatic increase in mean life span and life expectancy, coupled with a significant reduction in e...
Abstract The process of maintaining life for the individual is a constant struggle to preserve his/h...
During aging the immune system (IS) undergoes remarkable changes that collectively are known as immu...
The immune system defends against infection, but older people paradoxically suffer not only from fai...
A wide range of age-related alterations in immune system function have been described which contribu...
Recognising invading foreign organisms, preventing their spread and ultimately clearing them from th...
During the aging process, remodeling of several body systems occurs, and these changes can have a st...
There is evidence of declining effectiveness of the immune system with aging. This must reflect a di...
The immunosenescence is a relatively recent chapter, correlated with the linear extension of the ave...
Human aging is a multifactorial phenomenon that affects numerous organ systems and cellular processe...
Background: Evolutionary theory and empirical evidence suggest that aging is a process of gradual ac...
Adaptive immunity undergoes severe deterioration with age and represents the main problem in the eld...
The major changes occurring life long in the human immune system are here described. The progressive...
Major advances in preventing, delaying, or curing individual pathologies are responsible for an incr...
In the elderly, many alterations of innate and acquired immunity have been described and viewed as d...
A dramatic increase in mean life span and life expectancy, coupled with a significant reduction in e...
Abstract The process of maintaining life for the individual is a constant struggle to preserve his/h...
During aging the immune system (IS) undergoes remarkable changes that collectively are known as immu...
The immune system defends against infection, but older people paradoxically suffer not only from fai...
A wide range of age-related alterations in immune system function have been described which contribu...
Recognising invading foreign organisms, preventing their spread and ultimately clearing them from th...
During the aging process, remodeling of several body systems occurs, and these changes can have a st...
There is evidence of declining effectiveness of the immune system with aging. This must reflect a di...
The immunosenescence is a relatively recent chapter, correlated with the linear extension of the ave...
Human aging is a multifactorial phenomenon that affects numerous organ systems and cellular processe...
Background: Evolutionary theory and empirical evidence suggest that aging is a process of gradual ac...
Adaptive immunity undergoes severe deterioration with age and represents the main problem in the eld...