Among myeloid immune receptors, C-type lectin receptors (CLRs) have a remarkable capacity to sense a variety of self and non-self ligands. The coupling of CLRs to different signal transduction modules is influenced not only by the receptor, but also by the nature, density and architecture of the ligand, which can affect the rate of receptor internalization and trafficking to diverse intracellular compartments. Understanding how the variety of self and non-self ligands triggers differential CLR signalling and function presents a fascinating biological challenge. Non-self ligands usually promote inflammation and immunity, whereas self ligands are frequently involved in communication and tolerance. But pathogens can mimic self-inhibitory signa...
After both sterile and infectious insults, damage is inflicted on tissues leading to accidental or p...
It is now appreciated that the range of ligands interacting with C-type lectin type receptors on ant...
Item does not contain fulltextCarbohydrate-binding C-type lectin and lectin-like receptors play an i...
Among myeloid immune receptors, C-type lectin receptors (CLRs) have a remarkable capacity to sense a...
AbstractAmong myeloid immune receptors, C-type lectin receptors (CLRs) have a remarkable capacity to...
C-type lectin receptors (CLRs) comprise a heterogeneous group of transmembrane proteins. Many of the...
Myeloid C-type lectin receptors (CLRs) are important sensors of self and non-self that work in conce...
C-type lectins expressed on myeloid cells comprise a family of proteins that share a common structur...
C-type lectin receptors (CLRs) expressed by dendritic cells are crucial for tailoring immune respons...
Over the last decade, C-type lectin-like receptors (CTLRs), expressed mostly by myeloid cells, have ...
Pathogen recognition by C-type lectin receptors (CLRs) expressed by dendritic cells is important not...
Dendritic cells (DCs) are highly efficient antigen-presenting cells (APCs) that collect antigen in b...
Several spleen tyrosine kinase–coupled C-type lectin receptors (CLRs) have emerged as important patt...
AbstractC-type lectin receptors encoded by the natural killer gene complex play critical roles in en...
C-type lectin receptors (CLRs) comprise a large superfamily of proteins, which recognise a diverse r...
After both sterile and infectious insults, damage is inflicted on tissues leading to accidental or p...
It is now appreciated that the range of ligands interacting with C-type lectin type receptors on ant...
Item does not contain fulltextCarbohydrate-binding C-type lectin and lectin-like receptors play an i...
Among myeloid immune receptors, C-type lectin receptors (CLRs) have a remarkable capacity to sense a...
AbstractAmong myeloid immune receptors, C-type lectin receptors (CLRs) have a remarkable capacity to...
C-type lectin receptors (CLRs) comprise a heterogeneous group of transmembrane proteins. Many of the...
Myeloid C-type lectin receptors (CLRs) are important sensors of self and non-self that work in conce...
C-type lectins expressed on myeloid cells comprise a family of proteins that share a common structur...
C-type lectin receptors (CLRs) expressed by dendritic cells are crucial for tailoring immune respons...
Over the last decade, C-type lectin-like receptors (CTLRs), expressed mostly by myeloid cells, have ...
Pathogen recognition by C-type lectin receptors (CLRs) expressed by dendritic cells is important not...
Dendritic cells (DCs) are highly efficient antigen-presenting cells (APCs) that collect antigen in b...
Several spleen tyrosine kinase–coupled C-type lectin receptors (CLRs) have emerged as important patt...
AbstractC-type lectin receptors encoded by the natural killer gene complex play critical roles in en...
C-type lectin receptors (CLRs) comprise a large superfamily of proteins, which recognise a diverse r...
After both sterile and infectious insults, damage is inflicted on tissues leading to accidental or p...
It is now appreciated that the range of ligands interacting with C-type lectin type receptors on ant...
Item does not contain fulltextCarbohydrate-binding C-type lectin and lectin-like receptors play an i...