GENETIC EVIDENCE FOR LINEAGE- AND DIFFERENTIATION STAGE-RELATED CONTRIBUTION OF SOMATIC PTPN11 MUTATIONS TO LEUKEMOGENESIS IN CHILDHOOD ACUTE LEUKEMIA

Pathway Analysis of Genome-wide Association Study in Childhood Leukemia among Hispanics

Hsu, Ling-I
Briggs, Farren
Shao, Xiaorong
Metayer, Catherine
Wiemels, Joseph L
Chokkalingam, Anand P
Barcellos, Lisa F

May 2016

BackgroundThe incidence of acute lymphoblastic leukemia (ALL) is nearly 20% higher among Hispanics t...

Identification of prognostic genetic factors in pediatric T-cell acute lymphoblastic leukemia: prognostic genetic factors in pediatric T-ALL

Grotel, Martine

September 2008

textabstractHematopoiesis is a complex process in which primitive and undifferentiated stem cells mu...

MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures

te Kronnie Geertruy
Dell'Orto Marta
Zangrando Andrea
Basso Giuseppe

June 2009

Abstract Background The presence of MLL rearrangements in acute leukemia results in a complex number...

Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukomogenesis in childhood acute leukemia

TARTAGLIA M
MARTINELLI S
CAZZANIGA G
CORDEDDU V
IAVARONE I
SPINELLI M
PALMI C
CARTA C
PESSION A
ARICO M
MASERA G
SORCINI M
GELB BD
BIONDI A.
BASSO, GIUSEPPE

January 2004

SHP-2 is a protein tyrosine phosphatase functioning as signal transducer downstream to growth factor...

PTPN11 mutations in childhood acute lymphoblastic leukemia occur as a secondary event associated with high hyperdiploidy

Molteni, Cg
TE KRONNIE, Geertrudy
Bicciato, S
Villa, T
Tartaglia, M
Basso, Giuseppe
Biondi, A
Cazzaniga, G.

January 2010

Letter to the Editor Leukemia (2010) 24, 232\u2013235; doi:10.1038/leu.2009.200; published online 24...

Somatic PTPN11 mutations in childhood acute myeloid leukemia

M. TARTAGLIA
S. MARTINELLI
I. IAVARONE
G. CAZZANIGA
M. SPINELLI
E. GIARIN
V. PETRANGELI
C. CARTA
R. MASETTI
M. ARIC
F. LOCATELLI
M. SPRCINI
A. PESSION
A. BIONDI
BASSO, GIUSEPPE

January 2005

Somatic mutations in PTPN11, the gene encoding the transducer SHP-2, have emerged as a novel class o...

Molecular origin of childhood acute lymphoblastic leukemia

Waanders, Esmé
Jongmans, Marjolijn C.J.
Mullighan, Charles G.

March 2016

Our understanding of the genetic etiology of pediatric acute lymphoblastic leukemia (ALL) has advanc...

A Specific Pattern of Somatic Mutations Associates with Poor Prognosis Aneuploid Acute Myeloid Leukemia: Results from the European NGS-PTL Consortium

November 2017

none25sinonenoneSimonetti, Giorgia; Padella, Antonella; FARIA DO VALLE, Italo; Manfrini, Marco; Papa...

MLL partner genes drive distinct gene expression profiles and genomic alterations in pediatric acute myeloid leukemia: an AIEOP study.

July 2015

none18No abstract availablenonePigazzi M;Masetti R;Bresolin S;Beghin A;Di Meglio A;Gelain S;Trentin ...

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.

Ellinghaus E.
Stanulla M.
Richter G.
Ellinghaus D.
Te Kronnie G.
Cario G.
Cazzaniga G.
Horstmann M.
Panzer Grumayer R.
Cavé H.
Trka J.
Cinek O.
Teigler Schlegel A.
Elsharawy A.
Hasler R.
Nebel A.
Meissner B.
Bartram T.
Lescai F.
Giordan M.
Nurnberg P.
Heinzow B.
Zimmermann M.
Schreiber S.
Schrappe M.
Franke A.
FRANCESCHI, CLAUDIO

January 2012

Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia

Ellinghaus E.
Stanulla M.
Richter G.
Ellinghaus D.
Te Kronnie G.
Cario G.
Cazzaniga G.
Horstmann M.
Panzer Grumayer R.
Cave H.
Trka J.
Cinek O.
Teigler-Schlegel A.
Elsharawy A.
Hasler R.
Nebel A.
Meissner B.
Bartram T.
Lescai F.
Franceschi C.
Giordan M.
Nurnberg P.
Heinzow B.
Zimmermann M.
Schreiber S.
Schrappe M.
Franke A.

January 2012

Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...

Cytogenetics and molecular genetics of childhood leukemia

Chan, LC
Wan, TSK
Ma, SK

January 1999

Childhood leukemia is the commonest form of childhood cancer and represents clonal proliferation of ...

B lineage acute lymphoblastic leukemia transformation in a child with juvenile myelomonocytic leukemia, type 1 neurofibromatosis and monosomy of chromosome 7 - Possible implications in the leukemogenesis

Scrideli, C. A.
Baruffi, M. R.
Rogatto, Silvia Regina
Valera, E. T.
Defavery, R.
Tone, L. G.

April 2003

This report describes the case of an 8-month-old infant with a diagnosis of juvenile myelomonocytic ...

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression.

Kuiper, R.P.
Schoenmakers, E.F.P.M.
Reijmersdal, S.V. van
Hehir-Kwa, J.Y.
Geurts van Kessel, A.H.M.
Leeuwen, F.N. van
Hoogerbrugge, P.M.

January 2007

Contains fulltext : 52698.pdf (publisher's version ) (Closed access)Gross cytogene...

Germline PTPN11 mutation affecting exon 8 in a case of syndromic juvenile myelomonocytic leukemia

P. Prontera
F. Pantaleoni
S. Martinelli
E. Mastrodicasa
G. Stangoni
G. Barboni
M. Tartaglia
E. Donti
AVERSA, Franco

January 2011

Juvenile myelomonocitic leukemia (JMML) is an aggressive clonal myeloproliferative disorder (MPD) th...

Pathway Analysis of Genome-wide Association Study in Childhood Leukemia among Hispanics

Hsu, Ling-I
Briggs, Farren
Shao, Xiaorong
Metayer, Catherine
Wiemels, Joseph L
Chokkalingam, Anand P
Barcellos, Lisa F

May 2016

BackgroundThe incidence of acute lymphoblastic leukemia (ALL) is nearly 20% higher among Hispanics t...

Identification of prognostic genetic factors in pediatric T-cell acute lymphoblastic leukemia: prognostic genetic factors in pediatric T-ALL

Grotel, Martine

September 2008

textabstractHematopoiesis is a complex process in which primitive and undifferentiated stem cells mu...

MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures

te Kronnie Geertruy
Dell'Orto Marta
Zangrando Andrea
Basso Giuseppe

June 2009

Abstract Background The presence of MLL rearrangements in acute leukemia results in a complex number...

Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukomogenesis in childhood acute leukemia

TARTAGLIA M
MARTINELLI S
CAZZANIGA G
CORDEDDU V
IAVARONE I
SPINELLI M
PALMI C
CARTA C
PESSION A
ARICO M
MASERA G
SORCINI M
GELB BD
BIONDI A.
BASSO, GIUSEPPE

January 2004

SHP-2 is a protein tyrosine phosphatase functioning as signal transducer downstream to growth factor...

PTPN11 mutations in childhood acute lymphoblastic leukemia occur as a secondary event associated with high hyperdiploidy

Molteni, Cg
TE KRONNIE, Geertrudy
Bicciato, S
Villa, T
Tartaglia, M
Basso, Giuseppe
Biondi, A
Cazzaniga, G.

January 2010

Letter to the Editor Leukemia (2010) 24, 232\u2013235; doi:10.1038/leu.2009.200; published online 24...

Somatic PTPN11 mutations in childhood acute myeloid leukemia

M. TARTAGLIA
S. MARTINELLI
I. IAVARONE
G. CAZZANIGA
M. SPINELLI
E. GIARIN
V. PETRANGELI
C. CARTA
R. MASETTI
M. ARIC
F. LOCATELLI
M. SPRCINI
A. PESSION
A. BIONDI
BASSO, GIUSEPPE

January 2005

Somatic mutations in PTPN11, the gene encoding the transducer SHP-2, have emerged as a novel class o...

Molecular origin of childhood acute lymphoblastic leukemia

Waanders, Esmé
Jongmans, Marjolijn C.J.
Mullighan, Charles G.

March 2016

Our understanding of the genetic etiology of pediatric acute lymphoblastic leukemia (ALL) has advanc...

A Specific Pattern of Somatic Mutations Associates with Poor Prognosis Aneuploid Acute Myeloid Leukemia: Results from the European NGS-PTL Consortium

November 2017

none25sinonenoneSimonetti, Giorgia; Padella, Antonella; FARIA DO VALLE, Italo; Manfrini, Marco; Papa...

MLL partner genes drive distinct gene expression profiles and genomic alterations in pediatric acute myeloid leukemia: an AIEOP study.

July 2015

none18No abstract availablenonePigazzi M;Masetti R;Bresolin S;Beghin A;Di Meglio A;Gelain S;Trentin ...

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.

Ellinghaus E.
Stanulla M.
Richter G.
Ellinghaus D.
Te Kronnie G.
Cario G.
Cazzaniga G.
Horstmann M.
Panzer Grumayer R.
Cavé H.
Trka J.
Cinek O.
Teigler Schlegel A.
Elsharawy A.
Hasler R.
Nebel A.
Meissner B.
Bartram T.
Lescai F.
Giordan M.
Nurnberg P.
Heinzow B.
Zimmermann M.
Schreiber S.
Schrappe M.
Franke A.
FRANCESCHI, CLAUDIO

January 2012

Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia

Ellinghaus E.
Stanulla M.
Richter G.
Ellinghaus D.
Te Kronnie G.
Cario G.
Cazzaniga G.
Horstmann M.
Panzer Grumayer R.
Cave H.
Trka J.
Cinek O.
Teigler-Schlegel A.
Elsharawy A.
Hasler R.
Nebel A.
Meissner B.
Bartram T.
Lescai F.
Franceschi C.
Giordan M.
Nurnberg P.
Heinzow B.
Zimmermann M.
Schreiber S.
Schrappe M.
Franke A.

January 2012

Acute lymphoblastic leukemia (ALL) is a malignant disease of the white blood cells. The etiology of ...

Cytogenetics and molecular genetics of childhood leukemia

Chan, LC
Wan, TSK
Ma, SK

January 1999

Childhood leukemia is the commonest form of childhood cancer and represents clonal proliferation of ...

B lineage acute lymphoblastic leukemia transformation in a child with juvenile myelomonocytic leukemia, type 1 neurofibromatosis and monosomy of chromosome 7 - Possible implications in the leukemogenesis

Scrideli, C. A.
Baruffi, M. R.
Rogatto, Silvia Regina
Valera, E. T.
Defavery, R.
Tone, L. G.

April 2003

This report describes the case of an 8-month-old infant with a diagnosis of juvenile myelomonocytic ...

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression.

Kuiper, R.P.
Schoenmakers, E.F.P.M.
Reijmersdal, S.V. van
Hehir-Kwa, J.Y.
Geurts van Kessel, A.H.M.
Leeuwen, F.N. van
Hoogerbrugge, P.M.

January 2007

Contains fulltext : 52698.pdf (publisher's version ) (Closed access)Gross cytogene...

Germline PTPN11 mutation affecting exon 8 in a case of syndromic juvenile myelomonocytic leukemia

P. Prontera
F. Pantaleoni
S. Martinelli
E. Mastrodicasa
G. Stangoni
G. Barboni
M. Tartaglia
E. Donti
AVERSA, Franco

January 2011

Juvenile myelomonocitic leukemia (JMML) is an aggressive clonal myeloproliferative disorder (MPD) th...

Pathway Analysis of Genome-wide Association Study in Childhood Leukemia among Hispanics

Hsu, Ling-I
Briggs, Farren
Shao, Xiaorong
Metayer, Catherine
Wiemels, Joseph L
Chokkalingam, Anand P
Barcellos, Lisa F

May 2016

BackgroundThe incidence of acute lymphoblastic leukemia (ALL) is nearly 20% higher among Hispanics t...

Identification of prognostic genetic factors in pediatric T-cell acute lymphoblastic leukemia: prognostic genetic factors in pediatric T-ALL

Grotel, Martine

September 2008

textabstractHematopoiesis is a complex process in which primitive and undifferentiated stem cells mu...

MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures

te Kronnie Geertruy
Dell'Orto Marta
Zangrando Andrea
Basso Giuseppe

June 2009

Abstract Background The presence of MLL rearrangements in acute leukemia results in a complex number...

GENETIC EVIDENCE FOR LINEAGE- AND DIFFERENTIATION STAGE-RELATED CONTRIBUTION OF SOMATIC PTPN11 MUTATIONS TO LEUKEMOGENESIS IN CHILDHOOD ACUTE LEUKEMIA

Abstract

Extracted data

GENETIC EVIDENCE FOR LINEAGE- AND DIFFERENTIATION STAGE-RELATED CONTRIBUTION OF SOMATIC PTPN11 MUTATIONS TO LEUKEMOGENESIS IN CHILDHOOD ACUTE LEUKEMIA

Abstract

Extracted data

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