After the sequencing of whole genomes and the identification of the genes contained in them, one of the main challenges remaining is to understand the mechanisms that regulate the expression of genes within the genome in order to gain knowledge about structural, biochemical, physiological and behavioral characteristics of organisms. Some of these mechanisms are controlled by so-called Genetic Regulatory Networks (GRNs). Boolean networks can help model biological GRNs. In this paper, a genetic algorithm is used to make inferences in Boolean networks, in combination with the Quine-McCluskey algorithm, when not all the output states of the genes have been determined. This lack of information could be treated as "don't care" states. Genetic alg...
Boolean descriptions of gene regulatory networks can provide an insight into interactions between ge...
Abstract. In order to understand complex genetic regulatory networks researchers require automated f...
The great amount of gene expression data has brought a big challenge for the discovery of Gene Regul...
After the sequencing of whole genomes and the identification of the genes contained in them, one of ...
This thesis focuses on the topic of gene regulatory network inference and control based on the Boole...
The inference of Gene Regulatory Networks (GRNs) from time series gene expression data is an effecti...
This dissertation attempts to answer some of the vital questions involved in the genetic regulatory ...
There are lots of work for inferring genetic network architectures from state transition tables whi...
Key words: genetic automaton, regulatory pattern of gene network, mechanisms of expression gene reg...
Gene regulatory networks (GRNs) describe how a collection of genes governs the processes within a ce...
Systems biology studies complex systems which involve a large number of interacting entities such th...
Microarrays allow researchers to measure the expres-sion of every gene in simple organisms. Understa...
Bioinformatics and network biology provide exciting and challenging research and application areas f...
“The original publication is available at www.springerlink.com”. Copyright SpringerA genetic algorit...
Boolean-based method, despite of its simplicity, would be a more attractive approach for inferring a...
Boolean descriptions of gene regulatory networks can provide an insight into interactions between ge...
Abstract. In order to understand complex genetic regulatory networks researchers require automated f...
The great amount of gene expression data has brought a big challenge for the discovery of Gene Regul...
After the sequencing of whole genomes and the identification of the genes contained in them, one of ...
This thesis focuses on the topic of gene regulatory network inference and control based on the Boole...
The inference of Gene Regulatory Networks (GRNs) from time series gene expression data is an effecti...
This dissertation attempts to answer some of the vital questions involved in the genetic regulatory ...
There are lots of work for inferring genetic network architectures from state transition tables whi...
Key words: genetic automaton, regulatory pattern of gene network, mechanisms of expression gene reg...
Gene regulatory networks (GRNs) describe how a collection of genes governs the processes within a ce...
Systems biology studies complex systems which involve a large number of interacting entities such th...
Microarrays allow researchers to measure the expres-sion of every gene in simple organisms. Understa...
Bioinformatics and network biology provide exciting and challenging research and application areas f...
“The original publication is available at www.springerlink.com”. Copyright SpringerA genetic algorit...
Boolean-based method, despite of its simplicity, would be a more attractive approach for inferring a...
Boolean descriptions of gene regulatory networks can provide an insight into interactions between ge...
Abstract. In order to understand complex genetic regulatory networks researchers require automated f...
The great amount of gene expression data has brought a big challenge for the discovery of Gene Regul...