Hormones and peptides involved in glucose homeostasis are emerging as important modulators of neural plasticity. In this regard, increasing evidence shows that molecules such as insulin, insulin-like growth factor-I, glucagon-like peptide-1, and ghrelin impact on the function of the hippocampus, which is a key area for learning and memory. Indeed, all these factors affect fundamental hippocampal properties including synaptic plasticity (i.e., synapse potentiation and depression), structural plasticity (i.e., dynamics of dendritic spines), and adult neurogenesis, thus leading to modifications in cognitive performance. Here, we review the main mechanisms underlying the effects of glucose metabolism on hippocampal physiology. In particular, we...
AbstractMetabolic syndrome (MetS) is a global epidemic, which involves a spectrum of metabolic disor...
Metabolic syndrome (MetS) is a global epidemic, which involves a spectrum of metabolic disorders com...
Poor cognitive ability is a consequence of a wide variety of neurobehavioral disorders and is a grow...
Hormones and peptides involved in glucose homeostasis are emerging as important modulators of neural...
Hormones and peptides involved in glucose homeostasis are emerging as important modulators of neural...
Insulin is now established as a key regulator of brain mechanisms that include both glucose metaboli...
Insulin is a peptide hormone released by pancreatic cells that is known to regulate absorption of gl...
Insulin regulates glucose uptake and storage in peripheral tissues, and has been shown to act within...
Diabetes mellitus is associated with cognitive deficits and an increased risk of dementia, particula...
Structural deterioration and volume loss of the hippocampal formation is observed in many diseases a...
Diabetes mellitus is associated with cognitive deficits and an increased risk of dementia, particula...
Neuronal glucose uptake was thought to be independent of insulin, being facilitated by glucose trans...
The pathophysiological mechanisms intersecting metabolic and neurodegenerative disorders include ins...
In the last decade, much attention has been devoted to the effects of nutrient-related signals on br...
Over 93 million Americans are obese, a condition which also increases the risk for developing neuroc...
AbstractMetabolic syndrome (MetS) is a global epidemic, which involves a spectrum of metabolic disor...
Metabolic syndrome (MetS) is a global epidemic, which involves a spectrum of metabolic disorders com...
Poor cognitive ability is a consequence of a wide variety of neurobehavioral disorders and is a grow...
Hormones and peptides involved in glucose homeostasis are emerging as important modulators of neural...
Hormones and peptides involved in glucose homeostasis are emerging as important modulators of neural...
Insulin is now established as a key regulator of brain mechanisms that include both glucose metaboli...
Insulin is a peptide hormone released by pancreatic cells that is known to regulate absorption of gl...
Insulin regulates glucose uptake and storage in peripheral tissues, and has been shown to act within...
Diabetes mellitus is associated with cognitive deficits and an increased risk of dementia, particula...
Structural deterioration and volume loss of the hippocampal formation is observed in many diseases a...
Diabetes mellitus is associated with cognitive deficits and an increased risk of dementia, particula...
Neuronal glucose uptake was thought to be independent of insulin, being facilitated by glucose trans...
The pathophysiological mechanisms intersecting metabolic and neurodegenerative disorders include ins...
In the last decade, much attention has been devoted to the effects of nutrient-related signals on br...
Over 93 million Americans are obese, a condition which also increases the risk for developing neuroc...
AbstractMetabolic syndrome (MetS) is a global epidemic, which involves a spectrum of metabolic disor...
Metabolic syndrome (MetS) is a global epidemic, which involves a spectrum of metabolic disorders com...
Poor cognitive ability is a consequence of a wide variety of neurobehavioral disorders and is a grow...