Differences in blood and semen oxidative status in fertile and infertile men, and their relationship with sperm quality.

Reprod Biomed Online. 2012 Sep;25(3):300-6. doi: 10.1016/j.rbmo.2012.05.011. Epub 2012 May 30. Differences in blood and semen oxidative status in fertile and infertile men, and their relationship with sperm quality. Benedetti S1, Tagliamonte MC, Catalani S, Primiterra M, Canestrari F, De Stefani S, Palini S, Bulletti C. Author information Abstract Oxidative stress plays a fundamental role in the aetiology of male infertility by negatively affecting sperm quality and function. Assessment of blood and seminal plasma oxidative profiles might be a valuable tool to improve evaluation of sperm reproductive capacity and functional competence. This study examined the lipid-soluble antioxidant profile and levels of lipid peroxidation both in blood and seminal plasma samples of infertile and fertile males, in relation to semen parameters. Total antioxidant capacity (TAC) and vitamin E concentrations were significantly (P