BACKGROUND: Acute coronary syndrome (ACS) has an important impact in public health with high morbidity and mortality. Prothrombotic and proinflammatory states are involved in the pathogenesis of the disease. Plasminogen activator inhibitor-1 (PAI-1) is the major inhibitor of the fibrinolysis and also is part of immune response. The -844 G>A gene polymorphism is related to increased PAI-1 protein levels. The aim of the study is to evaluate the association of -844 G>A PAI-1 polymorphism with ACS. METHODS: A total of 646 individuals were recruited from Western Mexico: 350 unrelated healthy subjects and 296 patients with diagnosis of ACS. RESULTS: The most important risk factor in our population was hypertension, followed by smoking. The geneti...
Background: The circulating levels of plasminogen activator inhibitor type 1 (PAI-1) are increased i...
Background: Many genetic factors, including polymorphisms in the genes regulating blood coagulation ...
Plasminogen activator inhibitor-1 (PAI-1), a rapid inhibitor of tissue-type plasminogen activator, h...
BACKGROUND: Acute coronary syndrome (ACS) has an important impact in public health with high morbidi...
Background. Acute coronary syndrome (ACS) has an important impact in public health with high morbidi...
Type-1 plasminogen activator inhibitor (PAI-1) 4G/5G polymorphism may influence the PAI-1 expression...
Activation of inflammation and coagulation are closely related andmutually interdependent in myocard...
AbstractOBJECTIVESThe study was done to assess whether the common polymorphic allele (4G) of the pla...
The present study aimed at investigating the 4G/5G and -844G/A polymorphisms and plasma concentratio...
BackgroundMyocardial Infarction (MI) was reportedly precipitated by acquired and inherited risk fact...
BACKGROUND: Genetic predisposition is an important risk factor in coronary artery disease (CAD).This...
Several polymorphisms have been described in the PAI-1 gene including the -844 G/A and Hind III C/G ...
© 2022 by the authors.BACKGROUND: Genetic predisposition is an important risk factor in coronary art...
Introduction: Among the genetic factors for coronary artery diseases, PAI-1 4G/5G and ACE I/D polymo...
Background: Myocardial infarction involves the three processes of atheroma development, plaque ruptu...
Background: The circulating levels of plasminogen activator inhibitor type 1 (PAI-1) are increased i...
Background: Many genetic factors, including polymorphisms in the genes regulating blood coagulation ...
Plasminogen activator inhibitor-1 (PAI-1), a rapid inhibitor of tissue-type plasminogen activator, h...
BACKGROUND: Acute coronary syndrome (ACS) has an important impact in public health with high morbidi...
Background. Acute coronary syndrome (ACS) has an important impact in public health with high morbidi...
Type-1 plasminogen activator inhibitor (PAI-1) 4G/5G polymorphism may influence the PAI-1 expression...
Activation of inflammation and coagulation are closely related andmutually interdependent in myocard...
AbstractOBJECTIVESThe study was done to assess whether the common polymorphic allele (4G) of the pla...
The present study aimed at investigating the 4G/5G and -844G/A polymorphisms and plasma concentratio...
BackgroundMyocardial Infarction (MI) was reportedly precipitated by acquired and inherited risk fact...
BACKGROUND: Genetic predisposition is an important risk factor in coronary artery disease (CAD).This...
Several polymorphisms have been described in the PAI-1 gene including the -844 G/A and Hind III C/G ...
© 2022 by the authors.BACKGROUND: Genetic predisposition is an important risk factor in coronary art...
Introduction: Among the genetic factors for coronary artery diseases, PAI-1 4G/5G and ACE I/D polymo...
Background: Myocardial infarction involves the three processes of atheroma development, plaque ruptu...
Background: The circulating levels of plasminogen activator inhibitor type 1 (PAI-1) are increased i...
Background: Many genetic factors, including polymorphisms in the genes regulating blood coagulation ...
Plasminogen activator inhibitor-1 (PAI-1), a rapid inhibitor of tissue-type plasminogen activator, h...