Add to ORKGVariants of the functional polymorphism in the serotonin transporter (upstream regulatory region: 5-HTTLPR), the tryptophan hydroxylase (TPH), the monoamine oxidase A (MAO-A), and the dopamine receptor D4 (DRD4) genes have all been associated with mood disorders. The aim of this study was to test those hypotheses by using a family-based association approach. Both diagnoses and psychopathology were used for phenotype definitions. A total of 134 nuclear families with mood disorders, with probands affected by bipolar (n = 103) or major depressive (n = 58) disorders, were included in the study. All subjects were typed for the above-mentioned gene variants using polymerase chain reaction (PCR) technique. No significant transmission disequilibriu...
BACKGROUND: There has been growing evidence that temperamental traits, including affective temperame...
Association studies in outbred populations represent an important paradigm for investigation of comp...
The aim of this study was to investigate the possible involvement of genetic variation in serotonin ...
Variants of the functional polymorphism in the serotonin transporter (upstream regulatory region: 5-...
Gene variants exert a complex range of effects on human normal and abnormal behavior. We previously ...
Inheritable factors are known to play an important role in the risk for Bipolar disorder (BD) as wel...
The dopaminergic system has been implicated in the aetiology of mood disorders. We conducted family-...
The aim of the present study was to investigate tyrosine hydroxylase, catechol-O-methyl transferase ...
The aim of this study was to investigate the possible involvement of genetic variation in serotonin ...
Association analysis of candidate genes may represent a strategy for clarifying the genetic componen...
The pathogenesis of bipolar disorder may involve, at least in part, aberrations in serotonergic neur...
The pathogenesis of bipolar disorder may involve, at least in part, aberrations in serotonergic neur...
Association studies with candidate genes may contribute towards the understanding of the etiopathoge...
In a population-based association study, we tested the hypothesis that allelic variants of the human...
Background: It has been suggested that the dopaminergic system is involved in the pathophysiology of...
BACKGROUND: There has been growing evidence that temperamental traits, including affective temperame...
Association studies in outbred populations represent an important paradigm for investigation of comp...
The aim of this study was to investigate the possible involvement of genetic variation in serotonin ...
Variants of the functional polymorphism in the serotonin transporter (upstream regulatory region: 5-...
Gene variants exert a complex range of effects on human normal and abnormal behavior. We previously ...
Inheritable factors are known to play an important role in the risk for Bipolar disorder (BD) as wel...
The dopaminergic system has been implicated in the aetiology of mood disorders. We conducted family-...
The aim of the present study was to investigate tyrosine hydroxylase, catechol-O-methyl transferase ...
The aim of this study was to investigate the possible involvement of genetic variation in serotonin ...
Association analysis of candidate genes may represent a strategy for clarifying the genetic componen...
The pathogenesis of bipolar disorder may involve, at least in part, aberrations in serotonergic neur...
The pathogenesis of bipolar disorder may involve, at least in part, aberrations in serotonergic neur...
Association studies with candidate genes may contribute towards the understanding of the etiopathoge...
In a population-based association study, we tested the hypothesis that allelic variants of the human...
Background: It has been suggested that the dopaminergic system is involved in the pathophysiology of...
BACKGROUND: There has been growing evidence that temperamental traits, including affective temperame...
Association studies in outbred populations represent an important paradigm for investigation of comp...
The aim of this study was to investigate the possible involvement of genetic variation in serotonin ...