We discuss expectations for the absorption of high-energy gamma-rays by \u3b3\u3b3 pair production with intergalactic radiation fields (IRFs) at very high redshifts (z ~ 5-20), and the prospects thereof for probing the cosmic reionization era. For the evolving IRF, a semi-analytical model incorporating both Population II and Population III stars is employed, which is consistent with a wide variety of existing high-z observations including quasi-stellar object spectral measurements, Wilkinson Microwave Anisotropy Probe Thomson depth constraints, near-infrared source count limits, etc. We find that the ultraviolet IRF below the Lyman edge energy with intensities in the range of a few times 10-19ergcm-2s-1Hz-1sr-1 can cause appreciable attenua...