Effects of closed-loop intravenous anesthesia guided by the Bispectral index in adult patients on emergence delirium. A randomized controlled study
- Cotoia, Antonella
- Mirabella, Lucia
- Beck, Renata
- Matrella, Pompeo
- Assenzo, Valentina
- Chazot, Thierry
- Cinnella, Gilda
- Liu, Ngai
- Dambrosio, Michele
Publication date
January 2017
DOI Publisher
Edizioni Minerva Medica Language
EnglishAbstract
Emergence delirium (ED) is an acute change in cognition after general anesthesia (GA) occurring in operative room, recovery room or in postanesthesia care. The automated propofolremifentanil titration by Bispectral index (BIS) (AutoTIVA) avoids period of deep (BIS<40) anesthesia and could potentially decrease the ED. The aim of this study was to evaluate ED in surgical patients under AutoTIVA, manual titration of propofol-remifentanil (ManualTIVA) or volatile BIS-guided GA. Secondarly, we aimed to evaluate age-related postoperative Mini-Mental State Examination (MMSE) changes
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