Maturation of miRNAs by dicer is required in vertebrates for normal neural development. Here we report that dicer inactivation in Xenopus affects cell cycle progression, survival and timing of the generation of retinal cells, resulting in small retinas with lamination defects. In particular, dicer inactivation delays the exit from the cell cycle and the translation of key genes of late neurogenesis, highlighting a crucial role of miRNAs in retinal development
Degeneration of the retinal pigmented epithelium (RPE) and aberrant blood vessel growth in the eye a...
During development axons encounter a variety of choice points where they have to make appropriate pa...
During development axons encounter a variety of choice points where they have to make appropriate pa...
Maturation of miRNAs by dicer is required in vertebrates for normal neural development. Here we repo...
Maturation of miRNAs by dicer is required in vertebrates for normal neural development. Here we repo...
DICER1, a multidomain RNase III endoribonuclease, plays a critical role in microRNA (miRNA) and RNA-...
AbstractFMR1 and FXR1 are RNA binding proteins interacting with the miRNA-induced silencing complex,...
During development axons encounter a variety of choice points where they have to make appropriate pa...
The nervous system is an extraordinary array of different cell types that are generated at predictab...
AbstractFMR1 and FXR1 are RNA binding proteins interacting with the miRNA-induced silencing complex,...
The multidomain RNase III endoribonuclease DICER is required for the generation of most functional m...
MicroRNAs (miRNAs) are small double-stranded RNAs that, in vertebrates, function as negative regulat...
In this work, we explored the role of Dicer, an RNase III enzyme that is central to the production o...
SummaryDicer controls the biogenesis of microRNAs (miRNAs) and is essential for neurogenesis. Recent...
AbstractThe neural crest (NC) lineage gives rise to a wide array of cell types ranging from neurons ...
Degeneration of the retinal pigmented epithelium (RPE) and aberrant blood vessel growth in the eye a...
During development axons encounter a variety of choice points where they have to make appropriate pa...
During development axons encounter a variety of choice points where they have to make appropriate pa...
Maturation of miRNAs by dicer is required in vertebrates for normal neural development. Here we repo...
Maturation of miRNAs by dicer is required in vertebrates for normal neural development. Here we repo...
DICER1, a multidomain RNase III endoribonuclease, plays a critical role in microRNA (miRNA) and RNA-...
AbstractFMR1 and FXR1 are RNA binding proteins interacting with the miRNA-induced silencing complex,...
During development axons encounter a variety of choice points where they have to make appropriate pa...
The nervous system is an extraordinary array of different cell types that are generated at predictab...
AbstractFMR1 and FXR1 are RNA binding proteins interacting with the miRNA-induced silencing complex,...
The multidomain RNase III endoribonuclease DICER is required for the generation of most functional m...
MicroRNAs (miRNAs) are small double-stranded RNAs that, in vertebrates, function as negative regulat...
In this work, we explored the role of Dicer, an RNase III enzyme that is central to the production o...
SummaryDicer controls the biogenesis of microRNAs (miRNAs) and is essential for neurogenesis. Recent...
AbstractThe neural crest (NC) lineage gives rise to a wide array of cell types ranging from neurons ...
Degeneration of the retinal pigmented epithelium (RPE) and aberrant blood vessel growth in the eye a...
During development axons encounter a variety of choice points where they have to make appropriate pa...
During development axons encounter a variety of choice points where they have to make appropriate pa...