GAMBARAN HISTOPATOLOGI TESTIS MENCIT (Mus musculus) YANG DIPAPAR TIMBAL (Pb) SETELAH PEMBERIAN EKSTRAK BUAH BIT (Beta vulgaris L.)

The purpose of this study was to know histopathological features changes of mice testes exposed by Pb after given beet fruit extract (Beta vulgaris L.). The study was conducted in August - September, 2015 at the Department of Veterinary Pathology, Faculty of Veterinary Medicine, Airlangga University. Twenty-five male mice (Mus muculus) aged 90 days with 25-30 g of body weight were used. These animals were divided into five groups (K-, K +, P1, P2, and P3) respectively each consist of five. K- were treated with CMC Na 0,5% 0.1 ml / kg / day, K + were treated with a Pb 20 mg / kg / day, P1 were treated with the extract bits of fruit 200 mg / kg / day followed by Pb dosis 20 mg/ kg/ day oral administired, P2 were treated with the extract bits of fruit 400 mg / kg / day followed by Pb dosis 20 mg/ kg/ day oral administired, and P3 were treated with the extract bits of fruit 800 mg / kg / day followed by Pb dosis 20 mg/ kg/ day oral administired respectively. Data were compared using ANOVA test. The results showed that the dosage of beet fruit extract 200 mg / kg / day influenced to histopatological features of mice testes from exposed by Pb