Changes of right ventricle geometry, mechanics and function in patients with functional tricuspid regurgitation

The aim: To evaluate geometric changes of tricuspid valve (TV) and right ventricle (RV) as well as mechanical and functional changes of RV in patients with functional tricuspid regurgitation (fTR) and determine their association with fTR severity and different etiology of fTR based on 2D echocardiography. The objectives: 1) To evaluate geometric TV and RV changes and RV functional parameters in groups of different fTR severity. 2) To compare TV and RV geometric, mechanical and functional parameters in groups of different fTR etiology. Methods: We prospectively enrolled 45 patients with fTR. Depending on fTR etiology patients were divided into 2 groups: first group – patients who had fTR due to left – sided heart disease; second group – patients who had fTR due to precapillary pulmonary hypertension (PH). Patients underwent 2D resting transthoracic echocardiography and speckle tracking echocardiography. Left and right ventricle’s geometric and functional parameters, TV geometric parameters, quantitative and semi–quantitative indicators of functional TR severity and RV strain were evaluated. Statistical analysis was performed using IBM SPSS 24.0 program. Echocardiographic parameters between 2 groups were compared using the Stjudent T or Mann Whitney U criteria, between 3 groups – using Kruskal – Wallis criteria or one–dimensional dispersion analysis. Results: The average age of patients was 65.2±12.14 years. The echocardiographic parameters of RV (RV width: (p=0,012), RV length: (p=0,002) and RV diastolic (p