Correlation between toluene diisocyanate in air and urinary toluene diamine by air sampling methods

Toluene diisocyanate(TDI) has been known the materials which is induced occupational asthma, is mostly used by the materials of industrial polyurethane, excreted as toluene diamine(TDA) in case of occurring metabolism in the human body when it inhaled. This research is demonstrated to make scrutiny into efficiency of two differentways of sampling in comparison with the cocentration after make use of the open cassette holder and the modified 2-piece cassette holder which are originaly existing to doing sampling 2,4-TDI as 2,6 TDI in the air, and to present more adequate way to TDI sampling in the air and to present more adequate way to TDI sampling in the air from comparing concentration TDA in a worker´s urine with concentration of TDI which is being sampling each ways And this study want to grasp the influence for TDA excretion by exposing TDI from the general character of workers. The study was experimented on the 22 workers from the factory where is pperated paining work using by paints from poly urethane. This study was performed to identify the personal character of workers by using the questionnaire. analysed TDI from 44 sample each in the middle of morning and afternoon and TDA from the 17 workers by take their urine. Open cassette holder is manufactured to face the filter with the outside by remove the modified 2-piece cassette holder eliminated he middle of section and top of the upper holder. As a result of analysis, the concentration of TDI in the air is higher on the mokigied 2-piece cassette holder than the open cassette holder for sampling, There was no different on the concentration of urinary TDA by personal character. The concentration of TDI in the air had a relation with the concentration of urinary TDA no matter what kind of sampling method used, but the sampling by modified 2-piece cassette holder had more relation than sampling by open face cassette holder. As a result of this experiment, the concentration of TDI by sampling from the each cassette holder has shown to us significant relation with the concentration of urinary TDA.ope