A case of hepatocellular carcinoma with mandibular metastasis

Hepatocellular carcinoma (HCC) metastasis to the mandible is an unusual finding. A review of the literature showed only 45 cases have been reported so far in the world. However, only 1 case of mandibular metastasis of hepatocellular carcinoma has been reported in Korea. A patient complained right upper quadrant pain and buccal swelling. HCC was diagnosed by abdominal computed tomography (CT) and hepatic angiography. Facial bone CT showed a soft tissue mass lesion that was destroying bone at the left mandibular area. The histologic diagnosis of the mandibular lesion was metastatic HCC. Transarterial chemoembolization for the HCC and radiation therapy to the mandible were performed. Now the mandibular lesion is stable after these therapies. We report here on the second case of mandibular HCC metastasis in Korea along with a literature review.ope