Add to ORKGS100A14 is an EF-hand calcium-binding protein that has been reported to be involved in the progression of many malignancies. However, its role in ovarian cancer has not yet been clarified. In this study, we investigated the significance of S100A14 expression in epithelial ovarian cancers (EOCs) as well as it's mechanism of action. On both RNA and protein levels, S100A14 was overexpressed in transformed cells. Immunohistochemical staining demonstrated that S100A14 expression was associated with advanced stage (P<0.001) and poor tumor grade (P<0.001). Moreover, S100A14 overexpression was an independent prognostic factor for overall survival (HR = 4.53, P = 0.029). We also investigated S100A14's functional role by employing lentiviral-mediated...
S100 gene family is the largest subfamily of calcium binding proteins, expressed in tissue and cell-...
B-cell lymphomas are clinically, pathologically and molecularly heterogeneous diseases. Multiple stu...
The molecular mechanisms of endometrail cancer invasion are poorly understood. S100A4, a member of t...
Background/Aims: Osteosarcoma (OS) is the most common primary bone malignancy in children and young ...
Abstract Background Ovarian cancer is the leading cause of gynecological cancer-related mortality. T...
Metastasis-associated in colon cancer 1 (MACC1) and S100 calcium binding protein A4 (S100A4) are pro...
Cholangiocarcinoma (CCA) carries a severe prognosis because of its strong invasiveness and early met...
AbstractThe S100 proteins contain two EF-hand motifs and are of generally unknown function. One of t...
Objective The S100P protein stimulates cell proliferation and survival, thereby contributing to canc...
The function of S100A4, a member of the calcium-binding S100 protein family, has been associated wit...
Background S100P is a Ca2+ binding protein overexpressed in a variety of cancers, and thus, has bee...
The S100 gene family is the largest subfamily of calcium binding proteins of EF-hand type, expressed...
Background: Chemoresistance remains one of the obstacles to overcome in the treatment of breast canc...
S100P was recently found to be overexpressed in a variety of cancers and is considered a potential t...
The S100 gene family, which is composed of at least 24 members carrying the Ca2+ binding EF-hand mot...
S100 gene family is the largest subfamily of calcium binding proteins, expressed in tissue and cell-...
B-cell lymphomas are clinically, pathologically and molecularly heterogeneous diseases. Multiple stu...
The molecular mechanisms of endometrail cancer invasion are poorly understood. S100A4, a member of t...
Background/Aims: Osteosarcoma (OS) is the most common primary bone malignancy in children and young ...
Abstract Background Ovarian cancer is the leading cause of gynecological cancer-related mortality. T...
Metastasis-associated in colon cancer 1 (MACC1) and S100 calcium binding protein A4 (S100A4) are pro...
Cholangiocarcinoma (CCA) carries a severe prognosis because of its strong invasiveness and early met...
AbstractThe S100 proteins contain two EF-hand motifs and are of generally unknown function. One of t...
Objective The S100P protein stimulates cell proliferation and survival, thereby contributing to canc...
The function of S100A4, a member of the calcium-binding S100 protein family, has been associated wit...
Background S100P is a Ca2+ binding protein overexpressed in a variety of cancers, and thus, has bee...
The S100 gene family is the largest subfamily of calcium binding proteins of EF-hand type, expressed...
Background: Chemoresistance remains one of the obstacles to overcome in the treatment of breast canc...
S100P was recently found to be overexpressed in a variety of cancers and is considered a potential t...
The S100 gene family, which is composed of at least 24 members carrying the Ca2+ binding EF-hand mot...
S100 gene family is the largest subfamily of calcium binding proteins, expressed in tissue and cell-...
B-cell lymphomas are clinically, pathologically and molecularly heterogeneous diseases. Multiple stu...
The molecular mechanisms of endometrail cancer invasion are poorly understood. S100A4, a member of t...