The choice of reconstruction in hypopharynx cancer is dependent on oncologic needs of the situation. If the cervical or thoracic esophagus is involved in hypopharynx cancer, esophagectomy and gastric pull-up or jejunal free flap graft or colon interposition are indicated. Colon interposition for esophageal reconstruction in hypopharynx cancer is performed only in patients whose stomach cannot be used for reconstruction because of the postgastrectomised status or simultaneous gastric cancer. We have recently experienced a case of total pharyngo-laryngo-esophagectomy and colon interposition in a patient with hypopharynx cancer who had received subtotal gastrectomy due to stomach cancer in the past. We provided a review of the current literatu...