Octamer-binding factor 3/4 (Oct3/4) is one of the key regulators maintaining the pluripotency and self-renewal in embryonic stem cells and is involved in the developmental events. However, the functional significance of Oct3/4 remains to be clarified during tooth morphogenesis. This study aimed to examine the functional role of Oct3/4 in mouse. During tooth morphogenesis (E11-E16.5), Oct3/4-positive cells, detected by nuclear immunoreaction, increased in number, and subsequently, their immunoreaction shifted from the nucleus to the cytoplasm at the stage of cell differentiation (E18.5). Quantitative real-time PCR clearly demonstrated the relationship between isoforms of Oct3/4 and the in vivo cellular localization of Oct3/4, suggesting that...
peer reviewedOct4 and Oct5 are two mouse maternally expressed proteins binding to the octamer motif....
Background. Mouse dental mesenchymal cells (mDMCs) from tooth genus of cap or later stages are frequ...
Our previous studies have demonstrated that nuclear factor I-C (NFI-C) null mice developed short mol...
The root apex of the tooth elongates until the completion of root development. Although the signalin...
The root apex of the tooth elongates until the completion of root development. Although the signalin...
Although the role played by the core transcription factor network, which includes c-Myc, Klf4, Nanog...
10noAlthough the role played by the core transcription factor network, which includes c-Myc, Klf4, N...
Although the role played by the core transcription factor network, which includes c-Myc, Klf4, Nanog...
Although the role played by the core transcription factor network, which includes c-Myc, Klf4, Nanog...
The Pou domain containing transcription factor Oct4 is a well-established regulator of pluripotency ...
Recent studies have demonstrated the existence of dental stem cells in the continuously growing toot...
Human dental pulp stem cells (DPSCs), unique mesenchymal stem cells (MSCs) type, exhibit the charact...
SummaryThe Pou domain containing transcription factor Oct4 is a well-established regulator of plurip...
The Pou domain containing transcription factor Oct4 is a well-established regulator of pluripotency ...
Introduction. Infection and apoptosis are combined triggers for inflammation in dental tissues. Octa...
peer reviewedOct4 and Oct5 are two mouse maternally expressed proteins binding to the octamer motif....
Background. Mouse dental mesenchymal cells (mDMCs) from tooth genus of cap or later stages are frequ...
Our previous studies have demonstrated that nuclear factor I-C (NFI-C) null mice developed short mol...
The root apex of the tooth elongates until the completion of root development. Although the signalin...
The root apex of the tooth elongates until the completion of root development. Although the signalin...
Although the role played by the core transcription factor network, which includes c-Myc, Klf4, Nanog...
10noAlthough the role played by the core transcription factor network, which includes c-Myc, Klf4, N...
Although the role played by the core transcription factor network, which includes c-Myc, Klf4, Nanog...
Although the role played by the core transcription factor network, which includes c-Myc, Klf4, Nanog...
The Pou domain containing transcription factor Oct4 is a well-established regulator of pluripotency ...
Recent studies have demonstrated the existence of dental stem cells in the continuously growing toot...
Human dental pulp stem cells (DPSCs), unique mesenchymal stem cells (MSCs) type, exhibit the charact...
SummaryThe Pou domain containing transcription factor Oct4 is a well-established regulator of plurip...
The Pou domain containing transcription factor Oct4 is a well-established regulator of pluripotency ...
Introduction. Infection and apoptosis are combined triggers for inflammation in dental tissues. Octa...
peer reviewedOct4 and Oct5 are two mouse maternally expressed proteins binding to the octamer motif....
Background. Mouse dental mesenchymal cells (mDMCs) from tooth genus of cap or later stages are frequ...
Our previous studies have demonstrated that nuclear factor I-C (NFI-C) null mice developed short mol...
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