Antiviral activity of sirolimus in an HIV-positive kidney transplant recipient
- Alfano G.
- Fontana F.
- Mori G.
- VICARI, EMANUELA
- Dolci G.
- Franceschini E.
- Guaraldi G.
- Mussini C.
- Cappelli G.
DOIAbstract
Sirolimus (SIR) is a potent immunosuppressive agent with multiple proprieties. We report beneficial antiviral effects of SIR in an HIV-positive kidney transplant recipient who experienced low-level HIV-1 replication. The immunosuppressive agent was well tolerated by the patient, and no side effects were reported during follow-up. Despite immunosuppressive monotherapy, SIR ensured stable graft function
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