The members of the Src family of nonreceptor tyrosine kinases (SFKs) are implicated in multiple signaling processes that regulate key cellular functions, including proliferation, migration, differentiation, and survival. SFKs are activated by a large number of receptors for growth factors, cytokines, steroid hormones, G protein-coupled receptors, and also by adhesion proteins and other signaling partners. Through their common modular kinase an adapter protein domains, SFKs critically contribute to diversify different signal inputs, weaving a complex and dynamic network of cellular responses. Not surprisingly, SFKs are involved in embryo development and in the maintenance of different adult tissues and organs. Conversely, dysfunction of SFKs...
The Src family consists of eight non-receptor protein tyrosine kinases characterised by a common str...
Abstract Background The non-receptor tyrosine kinase,...
The non-receptor tyrosine kinase Csk serves as an indispensable negative regulator of the Src family...
Src family tyrosine kinases (SFKs) are involved in a diverse array of physiological processes, as hi...
Src is the prototypal member of Src Family tyrosine Kinases (SFKs), a large non-receptor kinase clas...
Protein kinases, either membrane-embedded receptorial or cytosolic non-receptorial ones, are importa...
Src is the representative member of the Src-family kinases (SFKs), a group of tyrosine kinases invol...
Prolactin (PRL) is a polypeptide hormone/cytokine mainly synthesized by the lactotrophic cells of th...
The Src family of protein kinases (SFKs), plays an important role in regulating the signal transduct...
Src-family kinases (SFKs) are structurally related non-receptor tyrosine kinases (Brickell, 1992). V...
The receptor tyrosine kinase FLT3 is expressed almost exclusively in the hematopoietic compartment. ...
Abstract Breast cancer (BC) has been ranked the most common malignant tumor throughout the world and...
The Src family protein tyrosine kinases (SFKs) are non-receptor intracellular kinases that have impo...
This article belongs to the Special Issue Biological Interfaces in Gastrointestinal Cancer.The proto...
The Src family consists of eight non-receptor protein tyrosine kinases characterised by a common str...
The Src family consists of eight non-receptor protein tyrosine kinases characterised by a common str...
Abstract Background The non-receptor tyrosine kinase,...
The non-receptor tyrosine kinase Csk serves as an indispensable negative regulator of the Src family...
Src family tyrosine kinases (SFKs) are involved in a diverse array of physiological processes, as hi...
Src is the prototypal member of Src Family tyrosine Kinases (SFKs), a large non-receptor kinase clas...
Protein kinases, either membrane-embedded receptorial or cytosolic non-receptorial ones, are importa...
Src is the representative member of the Src-family kinases (SFKs), a group of tyrosine kinases invol...
Prolactin (PRL) is a polypeptide hormone/cytokine mainly synthesized by the lactotrophic cells of th...
The Src family of protein kinases (SFKs), plays an important role in regulating the signal transduct...
Src-family kinases (SFKs) are structurally related non-receptor tyrosine kinases (Brickell, 1992). V...
The receptor tyrosine kinase FLT3 is expressed almost exclusively in the hematopoietic compartment. ...
Abstract Breast cancer (BC) has been ranked the most common malignant tumor throughout the world and...
The Src family protein tyrosine kinases (SFKs) are non-receptor intracellular kinases that have impo...
This article belongs to the Special Issue Biological Interfaces in Gastrointestinal Cancer.The proto...
The Src family consists of eight non-receptor protein tyrosine kinases characterised by a common str...
The Src family consists of eight non-receptor protein tyrosine kinases characterised by a common str...
Abstract Background The non-receptor tyrosine kinase,...
The non-receptor tyrosine kinase Csk serves as an indispensable negative regulator of the Src family...