Enzyme immobilization, an old-fashioned tool or a modern strategy to improve enzyme properties?

Enzymes are very promising biocatalysts, due to their high activity under mild conditions, high specificity and selectivity. However, due to their biological origin, enzymes have some drawbacks when used as industrial biocatalyst. They are water soluble molecules difficult to separate and recover in many instances, unstable under conditions far from the physiological ones, the high activity, selectivity and specificity refers to their physiological substrate, etc.Peer Reviewe