The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update
- Catassi, Carlo
- Alaedini, Armin
- Bojarski, Christian
- Bonaz, Bruno
- Bouma, Gerd
- Carroccio, Antonio
- Castillejo, Gemma
- De Magistris, Laura
- Dieterich, Walburga
- Di Liberto, Diana
- Elli, Luca
- Fasano, Alessio
- Hadjivassiliou, Marios
- Kurien, Matthew
- Lionetti, Elena
- Mulder, Chris
- Rostami, Kamran
- Sapone, Anna
- Scherf, Katharina
- Schuppan, Detlef
- Trott, Nick
- Volta, Umberto
- Zevallos, Victor
- Zopf, Yurdagül
- Sanders, David
DOIAbstract
Gluten-related disorders have recently been reclassified with an emerging scientific literature supporting the concept of non-celiac gluten sensitivity (NCGS). New research has specifically addressed prevalence, immune mechanisms, the recognition of non-immunoglobulin E (non-IgE) wheat allergy and overlap of NCGS with irritable bowel syndrome (IBS)-type symptoms. This review article will provide clinicians with an update that directly impacts on the management of a subgroup of their IBS patients whose symptoms are triggered by wheat ingestion
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