Fatal Septic Shock Associated with Herpes Simplex Virus Hepatitis: A Case Report.
- Inthasot, Valentine
- Goushchi, Adonis
- Lazzaroni, Silvia
- Papaleo, Alberto
- Gomez-Galdon, Maria
- Chochrad, Didier
DOIAbstract
Herpes simplex viruses are endemic worldwide, with an estimated seroprevalence of approximately 70% in developed countries. However, it is less well known that they are one of the viral causes of fulminant hepatitis (<2%) and constitute <1% of all causes of acute liver failure. We describe the case of an 89-year-old man who developed sepsis caused by a urinary tract infection due to drug-sensitive Escherichia coli. After empirical treatment with piperacillin-tazobactam was initiated, the patient's condition worsened with shock, acute liver and renal failure, encephalopathy and persistent fever, that led to admission to the intensive care unit. The emergence of an acute abdomen prompted exploratory laparotomy but the patient died soon after ...
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