Hepatoid Adenocarcinoma in Gallbladder: A Case Report

Hepatoid adenocarcinoma is a rare extrahepatic tumor, resembling hepatocellular carcinoma. It resembles hepatocytes both morphologically and functionally. Serum level of AFP is high in most cases. They reveal positive immunostaining with AFP, CEA, CK-8 and CK-18. To make the diagnosis of Hepatoid adenocarcinoma, hepatocellular carcinoma should be ruled out. Although it has an aggressive natural history, some cases like ours may show slower course, and recur in distant sites. In this article, we present a case of ovarian Hepatoid adenocarcinoma who presented with tumor in gallbladder having similar histopathology after 3 years of initial diagnosis