Bipolar disorder and pregnancy

Abstract Appendix Background: Bipolar Disorder and Postpartum Psychosis are serious conditions in pregnancy with implications from both illness and treatments for poorer pregnancy; neonatal and longer term developmental outcomes. Relapse rates without treatment are high and choice of treatment important to both keep women well and ensure minimal impact on offspring. Objectives: This paper will present both literature on the natural course for Bipolar Disorder and for Postpartum Psychosis in pregnancy and the early postpartum, treatment options and risks/benefits and management recommendations. Finally, data collected within a tertiary maternity hospital that has a specialized antenatal clinic for women with Schizophrenia and Bipolar Disorder will be presented. Methods: A review of literature and current guidelines across several services will be undertaken. Retrospective data drawn from a specialized antenatal clinic will be analyzed for pregnancy and neonatal complications. Findings: Bipolar Disorder and Postpartum Psychosis are both specifically associated with perinatal risks. However, the treatment recommendations for these two conditions differ across pregnancy and the postpartum. Conclusions: The further development of research and clinical guidance for management of Bipolar Disorder and Postpartum Psychosis is an important area of mental health to ensure better pregnancy and offspring outcomes