Add to ORKGOsteoarthritis is a propagated debilitating condition affecting patients' quality of life. Intra-articular injection approach was investigated as a localized treatment strategy providing: site-specific delivery, decreased side effects and, increased patient compliance. A 32 full factorial experimental design was employed to prepare the indomethacin-loaded self-assembling nanosystems (SANS). The surfactant (Poloxamer 407/Tetronic 90R4) ratio and the poly(lactic-co-glycolic acid) (PLGA) concentration significantly affected encapsulation efficiency and drug release (p<0.05). The optimized formula was subjected to modification by addition of different proteoglycans, as a compensatory treatment, to improve its pharmacological properties...
Tetramethylpyrazine (TMP) is a traditional Chinese herbal medicine with strong anti-inflammatory and...
My research focused on the treatment of osteoarthritis using injectable biomaterials. Osteoarthritis...
ABSTRACT: Arthritis is a major cause of disability conventionally treated for long term with nonster...
Many efforts have been made in the field of nanotechnology to improve the local and sustained releas...
Osteoarthritis (OA) is a chronic degenerative disease of the joint. Current treatments for this dise...
Purpose: The purpose of this study is to develop the nanoparticles that i) can be injected intra-art...
Osteoarthritis (OA), is a common musculoskeletal disorder that will progressively increase in older ...
Osteoarthritis (OA）is a common orthopaedic disease in middle-aged and aged people. To date, no disea...
Osteoarthritis (OA) is a degenerative joint disease. An objective of the nanomedicine and drug deliv...
As an emerging research direction, nanomedicine has been increasingly utilized to treat inflammatory...
Osteoarthritis (OA) is the most common type of arthritis affecting 80 % of the world's population ov...
As an emerging research direction, nanomedicine has been increasingly utilized to treat inflammatory...
Osteoarthritis (OA) is the most prevalent degenerative joint disease affecting millions of people wo...
Novel approach for intra-articular drug delivery: magnetically retainable biodegradable microparticl...
International audienceOsteoarthritis (OA) is the most common degenerative joint disease. Rapamycin i...
Tetramethylpyrazine (TMP) is a traditional Chinese herbal medicine with strong anti-inflammatory and...
My research focused on the treatment of osteoarthritis using injectable biomaterials. Osteoarthritis...
ABSTRACT: Arthritis is a major cause of disability conventionally treated for long term with nonster...
Many efforts have been made in the field of nanotechnology to improve the local and sustained releas...
Osteoarthritis (OA) is a chronic degenerative disease of the joint. Current treatments for this dise...
Purpose: The purpose of this study is to develop the nanoparticles that i) can be injected intra-art...
Osteoarthritis (OA), is a common musculoskeletal disorder that will progressively increase in older ...
Osteoarthritis (OA）is a common orthopaedic disease in middle-aged and aged people. To date, no disea...
Osteoarthritis (OA) is a degenerative joint disease. An objective of the nanomedicine and drug deliv...
As an emerging research direction, nanomedicine has been increasingly utilized to treat inflammatory...
Osteoarthritis (OA) is the most common type of arthritis affecting 80 % of the world's population ov...
As an emerging research direction, nanomedicine has been increasingly utilized to treat inflammatory...
Osteoarthritis (OA) is the most prevalent degenerative joint disease affecting millions of people wo...
Novel approach for intra-articular drug delivery: magnetically retainable biodegradable microparticl...
International audienceOsteoarthritis (OA) is the most common degenerative joint disease. Rapamycin i...
Tetramethylpyrazine (TMP) is a traditional Chinese herbal medicine with strong anti-inflammatory and...
My research focused on the treatment of osteoarthritis using injectable biomaterials. Osteoarthritis...
ABSTRACT: Arthritis is a major cause of disability conventionally treated for long term with nonster...