Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney disease remains reliant on extracorporeal hemodialysis (HD) in order to counter the lifelong complications of a failing kidney. While HD remains a life-saving option for these patients, mounting evidence suggests that it also fuels a vicious cycle of thromboinflammation that can increase the risk of cardiovascular disease. During HD, blood-borne innate immune systems become inappropriately activated on the biomaterial surface, instigating proinflammatory reactions that can alter endothelial and vascular homeostasis. Complement activation, early during the HD process, has been shown to fuel a multitude of detrimental thromboinflammatory reactions ...
Chronic kidney disease (CKD) is a growing health problem with a prevalence of approximately 10-15% w...
The aberrant activation of complement system in several kidney diseases suggests that this pillar of...
Complement deposition in the injured kidney is common, especially in glomerulonephritis. The precise...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. ...
Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. ...
Individuals receiving long-term hemodialysis are at increased risk of developing cardiovascular dise...
Complement components as uremic toxins and their potential role as mediators of microinflammation. C...
Significant advances have lead to a greater understanding of the role of the complement system withi...
Thrombosis is a common complication of end-stage renal disease, particularly in patients on hemodial...
Chronic kidney disease (CKD) is a growing health problem with a prevalence of approximately 10-15% w...
The aberrant activation of complement system in several kidney diseases suggests that this pillar of...
Complement deposition in the injured kidney is common, especially in glomerulonephritis. The precise...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
Owing to an increasing shortage of donor organs, the majority of patients with end-stage kidney dise...
Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. ...
Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. ...
Individuals receiving long-term hemodialysis are at increased risk of developing cardiovascular dise...
Complement components as uremic toxins and their potential role as mediators of microinflammation. C...
Significant advances have lead to a greater understanding of the role of the complement system withi...
Thrombosis is a common complication of end-stage renal disease, particularly in patients on hemodial...
Chronic kidney disease (CKD) is a growing health problem with a prevalence of approximately 10-15% w...
The aberrant activation of complement system in several kidney diseases suggests that this pillar of...
Complement deposition in the injured kidney is common, especially in glomerulonephritis. The precise...