Add to ORKGWe proposed an integrated and robust microfluidic platform to perform cell-based schedule dependent drug combination screening. Multiple manipulations of cells in droplets, including cell dispensing, culture, drug stimulation and viability test were performed based on a 2D microfluidic droplet array. The screening of flavopiridol (Fla) and 5-fluorouracil (5Flu) in different sequence was carried out in 342 addressable droplets, with a consumption of ∼3 μg drug for each experiment
Microfluidic devices present unique advantages for the development of efficient drug carrier particl...
Microfluidic techniques herald the arrival of a new era in biomedical experimentation, where new and...
Although the elementary unit of biology is the cell, high-throughput methods for the microscale mani...
We proposed an integrated and robust microfluidic platform to perform cell-based schedule dependent ...
We performed cell-based drug combination screening using an integrated droplet-based microfluidic sy...
In the last few decades, drug combination therapy has been widely applied in oncology and in other c...
Traditional high-throughput drug combination screening requires automatic pipetting of drugs into hi...
Screening is a fundamental process in today’s medicine and clinical diagnostics, comprising of sever...
[[abstract]]Combinational drug treatment has the potential of improving treatment efficacy, reducing...
Screening for potential drug combinations presents significant challenges to the current microfluidi...
[[abstract]]In vitro testing of drug compounds on cell models during the drug development process re...
Screening drugs on patient biopsies from solid tumours has immense potential, but is challenging due...
In the last decades, the basic techniques of microfluidics for the study of cells such as cell cultu...
Microfluidic devices present unique advantages for the development of efficient drug carrier particl...
Microfluidic techniques herald the arrival of a new era in biomedical experimentation, where new and...
Although the elementary unit of biology is the cell, high-throughput methods for the microscale mani...
We proposed an integrated and robust microfluidic platform to perform cell-based schedule dependent ...
We performed cell-based drug combination screening using an integrated droplet-based microfluidic sy...
In the last few decades, drug combination therapy has been widely applied in oncology and in other c...
Traditional high-throughput drug combination screening requires automatic pipetting of drugs into hi...
Screening is a fundamental process in today’s medicine and clinical diagnostics, comprising of sever...
[[abstract]]Combinational drug treatment has the potential of improving treatment efficacy, reducing...
Screening for potential drug combinations presents significant challenges to the current microfluidi...
[[abstract]]In vitro testing of drug compounds on cell models during the drug development process re...
Screening drugs on patient biopsies from solid tumours has immense potential, but is challenging due...
In the last decades, the basic techniques of microfluidics for the study of cells such as cell cultu...
Microfluidic devices present unique advantages for the development of efficient drug carrier particl...
Microfluidic techniques herald the arrival of a new era in biomedical experimentation, where new and...
Although the elementary unit of biology is the cell, high-throughput methods for the microscale mani...