Add to ORKGWe reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-gated calcium channels are risk genes for several disorders. Second, use of CCBs is associated with altered psychiatric risks and outcomes. Third, research shows there is an opportunity for brain-selective CCBs, which are better suited to psychiatric indications
Voltage-gated calcium channels (VGCCs) are widely expressed in the brain, heart and vessels, smooth ...
Background Recent breakthroughs in psychiatric genetics have implicated biological pathways onto wh...
Variations in the gene CACNA1C, which encodes the protein Cav1.2, has been identified as a risk fact...
We reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-gated cal...
A role for voltage-gated calcium channels (VGCCs) in psychiatric disorders has long been postulated ...
AbstractThis review summarises genetic studies in which calcium channel genes have been connected to...
Voltage-gated ion channels are important mediators of physiological functions in the central nervo...
This review summarises genetic studies in which calcium channel genes have been connected to the spe...
Calcium channel blockers (CCBs) differ in their ability to penetrate into the brain. Pharmacoepidemi...
Bipolar disorder (BD) is a common highly heritable disorder. The calcium channel gene family has bee...
abstract: Adolescent mental health problems are predicative of future problems such as depression, a...
Large-scale genome-wide association studies have consistently shown that genetic variation in CACNA1...
CACNA1C codes for the alpha-1 subunit of Cav1.2 L-type voltage gated calcium channels (LVGCCs). Vari...
Traditional genome-wide association studies (GWAS) have successfully detected genetic variants assoc...
Highlights A pilot study reports an association of polymorphisms of calcium channel genes and res...
Voltage-gated calcium channels (VGCCs) are widely expressed in the brain, heart and vessels, smooth ...
Background Recent breakthroughs in psychiatric genetics have implicated biological pathways onto wh...
Variations in the gene CACNA1C, which encodes the protein Cav1.2, has been identified as a risk fact...
We reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-gated cal...
A role for voltage-gated calcium channels (VGCCs) in psychiatric disorders has long been postulated ...
AbstractThis review summarises genetic studies in which calcium channel genes have been connected to...
Voltage-gated ion channels are important mediators of physiological functions in the central nervo...
This review summarises genetic studies in which calcium channel genes have been connected to the spe...
Calcium channel blockers (CCBs) differ in their ability to penetrate into the brain. Pharmacoepidemi...
Bipolar disorder (BD) is a common highly heritable disorder. The calcium channel gene family has bee...
abstract: Adolescent mental health problems are predicative of future problems such as depression, a...
Large-scale genome-wide association studies have consistently shown that genetic variation in CACNA1...
CACNA1C codes for the alpha-1 subunit of Cav1.2 L-type voltage gated calcium channels (LVGCCs). Vari...
Traditional genome-wide association studies (GWAS) have successfully detected genetic variants assoc...
Highlights A pilot study reports an association of polymorphisms of calcium channel genes and res...
Voltage-gated calcium channels (VGCCs) are widely expressed in the brain, heart and vessels, smooth ...
Background Recent breakthroughs in psychiatric genetics have implicated biological pathways onto wh...
Variations in the gene CACNA1C, which encodes the protein Cav1.2, has been identified as a risk fact...