Repetitive Behavior in Rubinstein–Taybi Syndrome: Parallels with Autism Spectrum Phenomenology

Background. Syndrome specific repetitive behavior profiles have been described previously. A detailed profile is absent for Rubinstein-Taybi syndrome (RTS). Method. The Repetitive Behaviour Questionnaire and Social Communication Questionnaire (SCQ) were completed for children and adults RTS (N = 87), Fragile-X (N = 196) and Down (N = 132) syndromes, and individuals reaching cut-off for Autism Spectrum Disorder (ASD) (N = 228). Results. Total and matched group analyses were conducted. A phenotypic profile of repetitive behavior was found in RTS. The majority of behaviors in RTS were not associated with social-communication deficits or degree of disability. Conclusions. Repetitive behavior should be studied at a fine-grained level. A dissociation of the triad of impairments might be evident in RTS