Towards real time radiotherapy simulation

We propose a novel reconfigurable hardware archi-tecture to implement Monte Carlo based simulation of physicaldose accumulation for intensity-modulated adaptive radiother-apy. The long term goal of our effort is to provide accurateonline dose calculation in real-time during patient treatment.This will allow wider adoption of personalised patient therapieswhich has the potential to significantly reduce dose exposureto the patient as well as shorten treatment and greatly reducecosts. The proposed architecture exploits the inherent parallelismof Monte Carlo simulations to perform domain decompositionand provide high resolution simulation without being limited byon-chip memory capacity. We present our architecture in detailand provide a performance model to estimate execution time,hardware area and bandwidth utilisation. Finally, we evaluateour architecture on a Xilinx VU9P platform and show that threecards are sufficient to meet our real time target of 100 millionrandomly generated particle histories per second