Exogenous human herpesvirus 6 reinfection after tumor-infiltrating T-lymphocyte therapy
- Filippova, Anastasiia
- Charles, Julie
- Epaulard, Olivier
- Germi, Raphaële
- Persoons, Virginie
- Templier, Isabelle
- Leccia, Marie-Thérèse
- Dreno, Brigitte
- Malova, Irina
- Morand, Patrice
- Lupo, Julien
DOIAbstract
International audienceExogenous human herpes virus 6 (HHV-6) reinfection has never been reported in patients receiving tumor-infiltrating T lymphocytes therapy. We report an unusual case of HHV-6 infection following infusion of HHV-6 infected autologous T lymphocytes. HHV-6 infection could interfere with the tumor antigen immune recognition and the efficacy of immunotherapy
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