Add to ORKGInternational audienceSuramin, a drug currently used for advanced malignancy, induces the differentiation of the human colonic adenocarcinoma cell clone HT29-D4 and this process is correlated with a decreased glycolytic activity. We investigated the effects of suramin on HT29-D4 cells in the presence of various glucose concentrations. The main result of this study is that suramin has only an effect on HT29-D4 cell growth and differentiation when the concentration of glucose is above 10 mM. Therefore the efficiency of suramin as an anticancer drug may be greater on poorly differentiated tumoral cells with a high proliferative capacity
AIMS AND BACKGROUND: Suramin has been shown to be of interest as a potential new anticancer agent be...
The effect of suramin on testosterone production was evaluated in cancer patients, adult male rats, ...
There are only a few experimental studies which have investigated effects of glucose alone, and gluc...
International audienceSuramin, a drug currently used for advanced malignancy, induces the differenti...
textabstractSuramin, a non‐specific growth factor antagonist, is currently under investigation for t...
Suramin, a polyanionic compound with known antiparasitic activity, has been shown to be adrenocortic...
AbstractProtein kinase C purified from rat brain was found to be inhibited by suramin, a substance u...
The present experiment was undertaken to study what types of human cancers are responsive to the ant...
This work studies the effects of suramin on the growth and morphology of cell strain U285, obtained ...
Objectives Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic...
Objectives: Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic...
Previous studies have shown that suramin is capable ofdisrupt-ing autocrine growth involving coexpre...
BACKGROUND: The results of conventional chemotherapy in metastatic colorectal cancer are discouragin...
Suramin has been shown to be of interest as a potential new anticancer agent because of its capacity...
Suramin has long been used for the treatment of Gambian and Rhodesian trypanosomiasis and oncocercia...
AIMS AND BACKGROUND: Suramin has been shown to be of interest as a potential new anticancer agent be...
The effect of suramin on testosterone production was evaluated in cancer patients, adult male rats, ...
There are only a few experimental studies which have investigated effects of glucose alone, and gluc...
International audienceSuramin, a drug currently used for advanced malignancy, induces the differenti...
textabstractSuramin, a non‐specific growth factor antagonist, is currently under investigation for t...
Suramin, a polyanionic compound with known antiparasitic activity, has been shown to be adrenocortic...
AbstractProtein kinase C purified from rat brain was found to be inhibited by suramin, a substance u...
The present experiment was undertaken to study what types of human cancers are responsive to the ant...
This work studies the effects of suramin on the growth and morphology of cell strain U285, obtained ...
Objectives Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic...
Objectives: Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic...
Previous studies have shown that suramin is capable ofdisrupt-ing autocrine growth involving coexpre...
BACKGROUND: The results of conventional chemotherapy in metastatic colorectal cancer are discouragin...
Suramin has been shown to be of interest as a potential new anticancer agent because of its capacity...
Suramin has long been used for the treatment of Gambian and Rhodesian trypanosomiasis and oncocercia...
AIMS AND BACKGROUND: Suramin has been shown to be of interest as a potential new anticancer agent be...
The effect of suramin on testosterone production was evaluated in cancer patients, adult male rats, ...
There are only a few experimental studies which have investigated effects of glucose alone, and gluc...